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喀麦隆引入疟疾疫苗:推广30天的早期结果

Malaria Vaccine Introduction in Cameroon: Early Results 30 Days into Rollout.

作者信息

Ndoula Shalom Tchokfe, Mboussou Frank, Njoh Andreas Ateke, Nembot Raoul, Baonga Simon Franky, Njinkeu Arnaud, Biey Joseph, Kaba Mohamed Ii, Amani Adidja, Farham Bridget, Kouontchou Mimbe Jean-Christian, Kouakam Christian Armel, Volkmann Konstantin, Dadjo Crépin Hilaire, Habimana Phanuel, Impouma Benido

机构信息

Expanded Program on Immunization, Ministry of Public Health, Yaoundé P.O. Box 1937, Cameroon.

World Health Organization Regional Office for Africa, Brazzaville P.O. Box 06, Congo.

出版信息

Vaccines (Basel). 2024 Mar 22;12(4):346. doi: 10.3390/vaccines12040346.

DOI:10.3390/vaccines12040346
PMID:38675729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11055092/
Abstract

Cameroon introduced the malaria vaccine in its routine immunization program on 22 January 2024 in the 42 districts out of 200 that are among the most at risk of malaria. A cross-sectional analysis of the data on key vaccine events in the introduction roadmap and the vaccine uptake during the first 30 days was conducted. In addition to available gray literature related to the introduction of the malaria vaccine, data on the malaria vaccine uptake by vaccination session, collected through a digital platform, were analyzed. A total of 1893 reports were received from 22 January 2024 to 21 February 2024 from 766 health facilities (84% of overall completeness). Two regions out of ten recorded less than 80% completeness. As of 21 February 2024, 13,811 children had received the first dose of the malaria vaccine, including 7124 girls (51.6%) and 6687 boys (48.4%). In total, 36% of the children were vaccinated through outreach sessions, while 61.5% were vaccinated through sessions in fixed posts. The overall monthly immunization coverage with the first dose was 37%. Early results have shown positive attitudes towards and acceptance of malaria vaccines. Suboptimal completeness of data reporting and a low coverage highlight persistent gaps and challenges in the vaccine rollout.

摘要

喀麦隆于2024年1月22日在其200个疟疾风险最高的地区中的42个地区,将疟疾疫苗纳入常规免疫计划。对引入路线图中关键疫苗事件的数据以及前30天的疫苗接种情况进行了横断面分析。除了与疟疾疫苗引入相关的现有灰色文献外,还分析了通过数字平台收集的按接种场次统计的疟疾疫苗接种数据。从2024年1月22日至2024年2月21日,共收到来自766家医疗机构的1893份报告(总体完整性为84%)。十个地区中有两个地区的完整性低于80%。截至2024年2月21日,13811名儿童接种了第一剂疟疾疫苗,其中包括7124名女孩(51.6%)和6687名男孩(48.4%)。总共有36%的儿童通过外展接种场次接种疫苗,而61.5%的儿童通过固定接种点的场次接种疫苗。第一剂疫苗的总体月度免疫覆盖率为37%。早期结果显示出对疟疾疫苗的积极态度和接受度。数据报告的完整性欠佳和覆盖率较低凸显了疫苗推广中持续存在的差距和挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/576f98abd743/vaccines-12-00346-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/91e162188903/vaccines-12-00346-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/136b222a687e/vaccines-12-00346-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/272c436adf2b/vaccines-12-00346-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/c38650726adb/vaccines-12-00346-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/67a8e9226c67/vaccines-12-00346-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/e21f499c8268/vaccines-12-00346-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/ad4a7c1b91d1/vaccines-12-00346-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/5de5471ce21d/vaccines-12-00346-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/576f98abd743/vaccines-12-00346-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/91e162188903/vaccines-12-00346-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/136b222a687e/vaccines-12-00346-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/272c436adf2b/vaccines-12-00346-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/c38650726adb/vaccines-12-00346-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/67a8e9226c67/vaccines-12-00346-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/e21f499c8268/vaccines-12-00346-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/ad4a7c1b91d1/vaccines-12-00346-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/5de5471ce21d/vaccines-12-00346-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed9/11055092/576f98abd743/vaccines-12-00346-g009.jpg

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本文引用的文献

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2
Perceptions around COVID-19 among patients and community members in urban areas in Cameroon: A qualitative perspective.喀麦隆城市地区患者和社区成员对新冠疫情的认知:定性研究视角
PLOS Glob Public Health. 2024 Feb 16;4(2):e0001760. doi: 10.1371/journal.pgph.0001760. eCollection 2024.
3
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Safety and efficacy of malaria vaccine candidate R21/Matrix-M in African children: a multicentre, double-blind, randomised, phase 3 trial.疟疾疫苗候选物 R21/Matrix-M 在非洲儿童中的安全性和有效性:一项多中心、双盲、随机、3 期临床试验。
Lancet. 2024 Feb 10;403(10426):533-544. doi: 10.1016/S0140-6736(23)02511-4. Epub 2024 Feb 1.
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Malaria.疟疾。
Lancet. 2023 Dec 16;402(10419):2328-2345. doi: 10.1016/S0140-6736(23)01249-7. Epub 2023 Nov 2.
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Assessment of immunization data management practices in Cameroon: unveiling potential barriers to immunization data quality.评估喀麦隆的免疫数据管理实践:揭示免疫数据质量的潜在障碍。
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