Moyadee Wassamon, Sunpongsri Supita, Choowongkomon Kiattawee, Roytrakul Sittiruk, Rattanasrisomporn Amonpun, Tansakul Natthasit, Rattanasrisomporn Jatuporn
Graduate Program in Animal Health and Biomedical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.
Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.
J Adv Vet Anim Res. 2024 Mar 12;11(1):19-26. doi: 10.5455/javar.2024.k742. eCollection 2024 Mar.
This study aimed to investigate the clinical and laboratory characteristics of naturally occurring feline infectious peritonitis (FIP) and estimate the median survival time of FIP cats treated with prednisolone to guide further therapeutic planning.
In this retrospective study, data from a total of 116 cats with effusion were fully recorded. Forty-five FIP-diagnosed cats were enrolled for analysis.
The study findings indicate that FIP was a disease affecting cats aged 1-2 years and was highly prevalent among male cats. Clinical manifestations of FIP affected the digestive (60%), hematological (53.3%), respiratory (33.3%), neurological (6.7%), and ocular (4.4%) systems. Blood profiles revealed mild anemia, lymphopenia, thrombocytopenia, hypoalbuminemia, hyperglobulinemia, and an albumin to globulin ratio of 0.4. Fluid analysis and cytology of FIP cats demonstrated a transparent yellow fluid with a protein content of 6 gm/dl and a total nucleated cell count of approximately 5,000-10,000 cells. During the observation period, FIP cats treated with prednisolone exhibited a median survival time of 31 days.
Confirming FIP cases can be challenging; therefore, a tentative diagnosis of FIP must be made with care. This study provided practical diagnostic tools to diagnose FIP based on clinical signs and multiple abnormalities, which allowed for more efficient and rapid detection.
本研究旨在调查自然发生的猫传染性腹膜炎（FIP）的临床和实验室特征，并估计接受泼尼松龙治疗的FIP猫的中位生存时间，以指导进一步的治疗规划。
在这项回顾性研究中，完整记录了总共116只出现积液的猫的数据。45只被诊断为FIP的猫被纳入分析。
研究结果表明，FIP是一种影响1 - 2岁猫的疾病，在雄性猫中高度流行。FIP的临床表现影响消化系统（60%）、血液系统（53.3%）、呼吸系统（33.3%）、神经系统（6.7%）和眼部系统（4.4%）。血液检查显示轻度贫血、淋巴细胞减少、血小板减少、低白蛋白血症、高球蛋白血症，白蛋白与球蛋白比值为0.4。FIP猫的液体分析和细胞学检查显示为透明黄色液体，蛋白质含量为6克/分升，总核细胞计数约为5000 - 10000个细胞。在观察期内，接受泼尼松龙治疗的FIP猫的中位生存时间为31天。
确诊FIP病例可能具有挑战性；因此，必须谨慎做出FIP的初步诊断。本研究提供了基于临床症状和多种异常情况诊断FIP的实用诊断工具，从而实现更高效、快速的检测。
