Du Ruo-Lan, Mauki David H, Zuo Zong-Fu
Department of Anatomy, Histology and Embryology Jinzhou Medical University Jinzhou Liaoning China.
National-Local Joint Engineering Research Center of Translational Medicine, West China Hospital Sichuan University Chengdu Sichuan China.
Ibrain. 2023 Dec 21;10(1):69-82. doi: 10.1002/ibra.12144. eCollection 2024 Spring.
Numerous brain diseases have been attributed to abnormalities in the connections of neural circuits. Exploration of neural circuits may give enlightenment in treating some intractable brain diseases. Here, we screened all publications on neural circuits in the Web of Science database from 2007 to 2022 and analyzed the research trends through VOSviewer, CiteSpace, Microsoft Excel 2019, and Origin. The findings revealed a consistent upward trend in research on neural circuits during this period. The United States emerged as the leading contributor, followed by China and Japan. Among the top 10 institutions with the largest number of publications, both the United States and China have a strong presence. Notably, the Chinese Academy of Sciences demonstrated the highest publication output, closely followed by Stanford University. In terms of influential authors, Karl Deisseroth stood out as one of the most prominent investigators. During this period, the majority of publications and citations on neural circuit research were found in highly influential journals including NEURON, NATURE JOURNAL OF NEUROSCIENCE, and so forth. Keyword clustering analysis highlighted the increasing focus on neural circuits and photogenetics in neuroscience research, and the reconstruction of neural circuits has emerged as a crucial research direction in brain science. In conclusion, over the past 15 years, the increasing high-quality publications have facilitated research development of neural circuits, indicating a promising prospect for investigations on neurological and psychiatric diseases.
许多脑部疾病都被认为与神经回路连接异常有关。对神经回路的探索可能会为治疗一些难治性脑部疾病带来启示。在此,我们筛选了科学网数据库中2007年至2022年关于神经回路的所有出版物,并通过VOSviewer、CiteSpace、Microsoft Excel 2019和Origin分析了研究趋势。研究结果显示,在此期间神经回路研究呈持续上升趋势。美国是主要贡献者,其次是中国和日本。在发表论文数量最多的前10家机构中,美国和中国都占据重要地位。值得注意的是,中国科学院的发表量最高,紧随其后的是斯坦福大学。在有影响力的作者方面,卡尔·戴瑟罗斯是最杰出的研究者之一。在此期间,神经回路研究的大多数出版物和引用都出现在包括《神经元》《自然神经科学杂志》等在内的高影响力期刊上。关键词聚类分析突出了神经科学研究中对神经回路和光遗传学的关注度不断提高,神经回路重建已成为脑科学的一个关键研究方向。总之,在过去15年里,高质量出版物的增加推动了神经回路的研究发展,表明神经和精神疾病研究前景广阔。