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[秘鲁利马市对环境真菌孢子的鉴定与致敏情况]

[Identification and sensitization to environmental fungal spores in Lima City, Peru].

作者信息

Calderón-Llosa Oscar Manuel

机构信息

Estación de Aerobiología, acreditada por la National Allergy Bureau (NAB) de la American Academy of Allergy, Asthma and Immunology (AAAAI), en la Clínica SANNA El Golf, San Isidro, Lima, Perú; Sub-Coordinador del Comité de Aerobiología de la Sociedad Latinoamericana de Alergia, Asma e Inmunología (SLAAI). Miembro del Comité de Aerobiología de la Sociedad Española de Alergología e Inmunología Clínica (SEAIC).

出版信息

Rev Alerg Mex. 2024 Feb 1;71(1):82. doi: 10.29262/ram.v71i1.1320.

DOI:10.29262/ram.v71i1.1320
PMID:38683099
Abstract

OBJECTIVE

To identify and registry the most important fungal spores trapped in our aerobiology station, as well as to report the prevalence of skin sensitization to these allergens.

METHODS

The pollen counts were made according to standardized technique with a Burkard seven days spore trap, following the American Academy of Allergy, Asthma and Immunology (AAAAI) through National Allergy Bureau (NAB) recommendations. The trap was installed on the roof of Clinica SANNA, El GOLF, San Isidro, which is 20 m high, 12°5'54"S 77°3'6"W in the west-south of the Lima urban area. The sampling period was performed from September 2020 to October 2021. Skin prick tests were carried out according to the recommendations of the Spanish Society of Allergology and Clinical Immunology (SEAIC) in 200 patients (18 to 60 years old) with symptoms of rhinoconjunctivitis and/or asthma, who were evaluated in the Allergology Service of Clinica SANNA el Golf. Allergenic extracts were applied, dust mites (), cat and dog danders, cockroach (Periplaneta americana), grass 6 mix, weed mix, molds (.), INMUNOTEK-Spain provided the extracts. We also tested other fungal allergens such as , a mixture of . from the DIATER-Argentina laboratory.

RESULTS

We identified spores of Dreschlera/Helmintosporum spp. The patients showed sensitization to (14%), . (13,5%), . (8%), (7%), (6%), (5,5%), . (3%), (2,5%).

CONCLUSIONS

The inhabitants of the south-western area of the urban city of Lima are exposed to different fungal spores with allergenic potential, with a higher concentration being identified during the summer/autumn months. Cutaneous sensitization is demonstrated in variable percentages to the fungal spores identified in this aerobiological sampling. The results of this study should be expanded and compared with data in the forthcoming years, identify seasonal and annual fluctuations and extend the traps to other locations in Lima.

摘要

目的

识别并记录困在我们空气生物学监测站的最重要的真菌孢子,同时报告对这些过敏原皮肤致敏的发生率。

方法

花粉计数采用标准化技术,使用伯卡德七天孢子捕捉器,遵循美国过敏、哮喘与免疫学会(AAAAI)通过国家过敏局(NAB)给出的建议。捕捉器安装在位于利马市区西南方向、海拔20米、南纬12°5′54″、西经77°3′6″的圣伊西德罗埃尔戈尔夫的桑纳诊所屋顶。采样期为2020年9月至2021年10月。根据西班牙变态反应学和临床免疫学学会(SEAIC)的建议,对200名(年龄在18至60岁之间)有鼻结膜炎和/或哮喘症状、在桑纳诊所埃尔戈尔夫变态反应科接受评估的患者进行皮肤点刺试验。应用了变应原提取物,包括尘螨()、猫和狗的皮屑、蟑螂(美洲大蠊)、6种混合草类、杂草混合物、霉菌(.),由西班牙INMUNOTEK公司提供提取物。我们还测试了其他真菌过敏原,如来自阿根廷DIATER实验室的、的混合物。

结果

我们识别出德氏霉属/长蠕孢属真菌的孢子。患者对(14%)、.(13.5%)、.(8%)、(7%)、(6%)、(5.5%)、.(3%)、(2.5%)表现出致敏。

结论

利马市区西南部居民接触到具有变应原潜力的不同真菌孢子,在夏/秋季节浓度更高。在本次空气生物学采样中识别出的真菌孢子,不同比例的患者表现出皮肤致敏。本研究结果应在未来几年进行扩展并与数据进行比较,识别季节性和年度波动情况,并将捕捉器扩展到利马的其他地点。

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