Zhang Zejun, Shi Fan, Ai Yijing, Li Xiaoqing, Zhang Dan, Wang Lisi, Sun Wei
Hainan Engineering Research Center of Tropical Ocean Advanced Optoelectronic Functional Materials, Hainan International Joint Research Center of Marine Advanced Photoelectric Functional Materials, Key Laboratory of Laser Technology and Optoelectronic Functional Materials of Hainan Province, Key Laboratory of Functional Materials and Photoelectrochemistry of Haikou, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, 571158, China.
College of Chemistry and Chemical Engineering, Zhaotong University, Zhaotong, 657000, China.
Mikrochim Acta. 2024 Apr 29;191(5):290. doi: 10.1007/s00604-024-06298-0.
A core-shell ZIF-67@ZIF-8-derived Co nanoparticles embedded in N-doped carbon nanotube polyhedra (Co/C-NCNP) hybrid nanostructure was prepared by a pyrolysis method. The synthesized Co/C-NCNP was modified on the screen-printed carbon electrode and used for the portable wireless sensitive determination of breviscapine (BVC) by differential pulse voltammetry. The Co/C-NCNP had a large surface area and excellent catalytic activity with increasing Co sites to combine with BVC for selective determination, which led to the improvement of the sensitivity of the electrochemical sensor. Under optimized conditions, the constructed sensor had linear ranges from 0.15 to 20.0 µmol/L and 20.0 to 100.0 µmol/L with the limit of detection of 0.014 µmol/L (3S/S). The sensor was successfully applied to BVC tablet sample analysis with satisfactory results. This work provided the potential applications of zeolitic imidazolate framework-derived nanomaterials in the fabrication of electrochemical sensors for the sensitive detection of drug samples.
通过热解方法制备了一种嵌入氮掺杂碳纳米管多面体（Co/C-NCNP）杂化纳米结构中的核壳型ZIF-67@ZIF-8衍生钴纳米颗粒。将合成的Co/C-NCNP修饰在丝网印刷碳电极上，并用于通过差分脉冲伏安法对灯盏花素（BVC）进行便携式无线灵敏测定。Co/C-NCNP具有大表面积和优异的催化活性，随着钴位点的增加可与BVC结合用于选择性测定，这导致了电化学传感器灵敏度的提高。在优化条件下，构建的传感器线性范围为0.15至20.0 μmol/L和20.0至100.0 μmol/L，检测限为0.014 μmol/L（3S/S）。该传感器成功应用于BVC片剂样品分析，结果令人满意。这项工作为沸石咪唑酯骨架衍生的纳米材料在制造用于灵敏检测药物样品的电化学传感器方面提供了潜在应用。
