Doctor of Philosophy Program in Social, Economic, and Administrative Pharmacy, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
BMJ Open. 2024 Apr 29;14(4):e079829. doi: 10.1136/bmjopen-2023-079829.
Several prevalence-based cost-of-illness (COI) studies have been conducted to estimate the economic burden of alcohol consumption borne by a particular society in a given year. Yet there are few studies examining the economic costs incurred by an individual drinker over his/her lifetime. Thus, this study aims to estimate the costs incurred by an individual drinker's alcohol consumption over his or her lifetime in Thailand.
An incidence-based COI approach will be employed. To project individuals' associated costs over a lifetime, a Markov modelling technique will be used. The following six alcohol-related diseases/conditions will be considered in the model: hypertension, haemorrhagic stroke, liver cirrhosis, liver cancer, alcohol use disorders and road injury. The analysis will cover both direct (ie, direct healthcare cost, costs of property damage due to road traffic accidents) and indirect costs (ie, productivity loss due to premature mortality and hospital-related absenteeism). The human capital approach will be adopted to estimate the cost of productivity loss. All costs will be presented in Thai baht, 2022.
The Institutional Review Board of Mahidol University, Faculty of Dentistry/Faculty of Pharmacy has confirmed that no ethical approval is required (COE.No.MU-DT/PY-IRB 2021/010.0605). Dissemination of the study findings will be carried out through peer-reviewed publications, conferences and engagement with policy-makers and public health stakeholders.
已有多项基于患病率的疾病负担（COI）研究旨在估算特定社会在特定年份因酒精消费而产生的经济负担。然而，很少有研究关注个体终生因饮酒而产生的经济成本。因此，本研究旨在估算泰国个体终生因饮酒而产生的经济成本。
本研究将采用基于发生率的 COI 方法。为了预测个体终生的相关成本，将使用马尔可夫模型技术。该模型将考虑以下六种与酒精相关的疾病/状况：高血压、出血性中风、肝硬化、肝癌、酒精使用障碍和道路伤害。分析将涵盖直接成本（即直接医疗保健成本、因道路交通事故造成的财产损失成本）和间接成本（即因过早死亡和与医院相关的缺勤导致的生产力损失）。将采用人力资本法估算生产力损失的成本。所有成本均以 2022 年泰铢呈现。
玛希隆大学牙科学院/药学院的机构审查委员会已确认无需伦理批准（COE.No.MU-DT/PY-IRB 2021/010.0605）。将通过同行评审出版物、会议以及与政策制定者和公共卫生利益相关者的互动来传播研究结果。
