Institute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Chemnitzer Str. 46, 01187, Dresden, Germany.
Center for Interdisciplinary Addiction Research (ZIS), Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf (UKE), Martinistraße 52, 20246, Hamburg, Germany.
Pharmacoeconomics. 2021 Jul;39(7):809-822. doi: 10.1007/s40273-021-01031-8. Epub 2021 May 10.
Alcohol-attributable costs to society are captured by cost-of-illness studies, however estimates are often not comparable, e.g. due to the omission of relevant cost components. In this contribution we (1) summarize the societal costs attributable to alcohol use, and (2) estimate the total costs under the assumption that all cost components are considered.
A systematic review and meta-analyses were conducted for studies reporting costs from alcohol consumption for the years 2000 and later, using the EMBASE and MEDLINE databases. Cost estimates were converted into 2019 international dollars (Int$) per adult and into percentage of gross domestic product (GDP). For each study, weights were calculated to correct for the exclusion of cost indicators.
Of 1708 studies identified, 29 were included, and the mean costs of alcohol use amounted to 817.6 Int$ per adult (95% confidence interval [CI] 601.8-1033.4), equivalent to 1.5% of the GDP (95% CI 1.2-1.7%). Adjusting for omission of cost components, the economic costs of alcohol consumption were estimated to amount to 1306 Int$ per adult (95% CI 873-1738), or 2.6% (95% CI 2.0-3.1%) of the GDP. About one-third of costs (38.8%) were incurred through direct costs, while the majority of costs were due to losses in productivity (61.2%).
The identified cost studies were mainly conducted in high-income settings, with high heterogeneity in the employed methodology. Accounting for some methodological variations, our findings demonstrate that alcohol use continues to incur a high level of cost to many societies.
PROSPERO #CRD42020139594.
疾病成本研究捕捉了社会因酒精而产生的成本,但这些估计往往不可比,例如由于遗漏了相关成本组成部分。在本研究中,我们(1)总结了与酒精使用相关的社会成本,(2)在假设考虑所有成本组成部分的情况下,估算了总费用。
使用 EMBASE 和 MEDLINE 数据库对报告 2000 年及以后年份因饮酒导致的成本的研究进行了系统综述和荟萃分析。将成本估计数转换为每位成年人的 2019 年国际元(Int$)和国内生产总值(GDP)的百分比。对于每项研究,都计算了权重以纠正排除成本指标的影响。
在确定的 1708 项研究中,有 29 项被纳入,酒精使用的平均成本为每位成年人 817.6 Int$(95%置信区间[CI]为 601.8-1033.4),相当于 GDP 的 1.5%(95%CI 为 1.2-1.7%)。调整因遗漏成本组成部分而导致的偏差后,估计因饮酒而导致的经济成本为每位成年人 1306 Int$(95%CI 为 873-1738),或 GDP 的 2.6%(95%CI 为 2.0-3.1%)。约三分之一的成本(38.8%)是通过直接成本产生的,而大部分成本是由于生产力损失(61.2%)造成的。
所确定的成本研究主要在高收入环境中进行,所采用的方法存在很大的异质性。在考虑了一些方法学差异后,我们的研究结果表明,酒精使用继续给许多社会带来高昂的成本。
PROSPERO #CRD42020139594。