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Treating a type 2 diabetic patient with impaired pancreatic islet function by personalized endoderm stem cell-derived islet tissue.

作者信息

Wu Jiaying, Li Tuo, Guo Meng, Ji Junsong, Meng Xiaoxi, Fu Tianlong, Nie Tengfei, Wei Tongkun, Zhou Ying, Dong Weihua, Zhang Ming, Shi Yongquan, Cheng Xin, Yin Hao

机构信息

Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.

Department of Endocrinology, Shanghai Changzheng Hospital (Second Affiliated Hospital of Naval Medical University), Shanghai, China.

出版信息

Cell Discov. 2024 Apr 30;10(1):45. doi: 10.1038/s41421-024-00662-3.

DOI:10.1038/s41421-024-00662-3
PMID:38684699
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11058776/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e990/11058776/fda0f743a081/41421_2024_662_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e990/11058776/fda0f743a081/41421_2024_662_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e990/11058776/fda0f743a081/41421_2024_662_Fig1_HTML.jpg

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Lancet Diabetes Endocrinol. 2022 Jul;10(7):519-532. doi: 10.1016/S2213-8587(22)00114-0. Epub 2022 May 16.
2
Insulin expression and C-peptide in type 1 diabetes subjects implanted with stem cell-derived pancreatic endoderm cells in an encapsulation device.在封装装置中植入干细胞衍生的胰腺内胚层细胞的 1 型糖尿病患者的胰岛素表达和 C 肽。
Cell Rep Med. 2021 Dec 2;2(12):100466. doi: 10.1016/j.xcrm.2021.100466. eCollection 2021 Dec 21.
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Implanted pluripotent stem-cell-derived pancreatic endoderm cells secrete glucose-responsive C-peptide in patients with type 1 diabetes.
糖尿病的干细胞治疗：进展、前景与挑战。
World J Diabetes. 2025 Jul 15;16(7):107344. doi: 10.4239/wjd.v16.i7.107344.
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Regen Ther. 2025 Jul 5;30:341-350. doi: 10.1016/j.reth.2025.06.015. eCollection 2025 Dec.
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