职业与北欧国家的舌癌。

Occupation and tongue cancer in Nordic countries.

机构信息

Department of Oral and Maxillofacial Diseases, Clinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

Translational Immunology Research Program (TRIMM), University of Helsinki, Helsinki, Finland.

出版信息

BMC Oral Health. 2024 Apr 29;24(1):506. doi: 10.1186/s12903-024-04172-2.

DOI:10.1186/s12903-024-04172-2

PMID:38685000

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11059716/

Abstract

PURPOSE

Almost 200,000 tongue cancers were diagnosed worldwide in 2020. The aim of this study was to describe occupational risk variation in this malignancy.

METHODS

The data are based on the Nordic Occupational Cancer (NOCCA) study containing 14.9 million people from the Nordic countries with 9020 tongue cancers diagnosed during 1961-2005. The standardized incidence ratio (SIR) of tongue cancer in each occupational category was calculated using national incidence rates as the reference.

RESULTS

Among men, the incidence was statistically significantly elevated in waiters (SIR 4.36, 95% confidence interval (CI) 3.13--5.92), beverage workers (SIR 3.42, 95% CI 2.02-5.40), cooks and stewards (SIR 2.55, 95% CI 1.82-3.48), seamen (SIR 1.66, 95% CI 1.36-2.00), journalists (SIR 1.85, 95% CI 1.18-2.75), artistic workers (SIR 2.05, 95% CI 1.54-2.66), hairdressers (SIR 2.17, 95% CI 1.39-3.22), and economically inactive persons (SIR 1.57, 95% CI 1.42-1.73). Among women, the SIR was statistically significantly elevated only in waitresses (SIR 1.39, 95% CI 1.05-1.81). Statistically significant SIRs ≤ 0.63 were observed in male farmers, gardeners, forestry workers and teachers, and in female launderers.

CONCLUSIONS

These findings may be related to consumption of alcohol and tobacco, but the effect of carcinogenic exposure from work cannot be excluded.

摘要

目的

2020 年全球诊断出近 20 万例舌癌。本研究旨在描述这种恶性肿瘤的职业风险变化。

方法

数据基于北欧职业癌症（NOCCA）研究，该研究包含来自北欧国家的 1490 万人，1961-2005 年间诊断出 9020 例舌癌。使用国家发病率作为参考，计算每个职业类别的舌癌标准化发病比（SIR）。

结果

在男性中，服务员（SIR 4.36，95%置信区间（CI）3.13-5.92）、饮料工人（SIR 3.42，95%CI 2.02-5.40）、厨师和管家（SIR 2.55，95%CI 1.82-3.48）、海员（SIR 1.66，95%CI 1.36-2.00）、记者（SIR 1.85，95%CI 1.18-2.75）、艺术工作者（SIR 2.05，95%CI 1.54-2.66）、理发师（SIR 2.17，95%CI 1.39-3.22）和非经济活动人员（SIR 1.57，95%CI 1.42-1.73）的发病率呈统计学显著升高。在女性中，仅服务员的 SIR 呈统计学显著升高（SIR 1.39，95%CI 1.05-1.81）。男性农民、园丁、林业工人和教师，以及女性洗衣工的 SIR 呈统计学显著降低（≤0.63）。