北欧国家的职业与膀胱癌风险

Occupation and Risk of Bladder Cancer in Nordic Countries.

作者信息

Hadkhale Kishor, Martinsen Jan Ivar, Weiderpass Elisabete, Kjaerheim Kristina, Lynge Elsebeth, Sparen Pär, Tryggvadottir Laufey, Pukkala Eero

机构信息

School of Health Sciences, University of Tampere, Finland (Mr Hadkhale, Dr Pukkala); Department of Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo (Mr Martinsen, Dr Weiderpass, Dr Kjaerheim); Department of Community Medicine, Faculty of Health Sciences, University of Troms⊘, The Arctic University of Norway (Dr Weiderpass); Genetic Epidemiology Group, Folkhälsan Research Center (Dr Weiderpass); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (Dr Weiderpass, Dr Sparen); Center for Epidemiology and Screening, Institute of Public Health, University of Copenhagen, Denmark (Dr Lynge); Icelandic Cancer Registry, Reykjavik, Iceland (Dr Tryggvadottir); and Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research (Dr Pukkala), Helsinki, Finland.

出版信息

J Occup Environ Med. 2016 Aug;58(8):e301-7. doi: 10.1097/JOM.0000000000000803.

DOI:10.1097/JOM.0000000000000803

PMID:27294445

Abstract

OBJECTIVE

The purpose of the study was to describe the variation of bladder cancer incidence according to occupational categories in the Nordic countries.

METHODS

The study cohort comprised 15 million individuals older than 30 years who participated in one or more population censuses in 1960, 1970, 1980/1981, and/or 1990. Standardized incidence ratios (SIRs) were estimated for 53 occupational categories.

RESULTS

Significantly increased SIRs were observed among tobacco workers (1.57; 95% confidence interval [CI] 1.24 to 1.96), chimney sweeps (1.48; 95% CI 1.21 to 1.80), waiters (1.43; 95% CI 1.33 to 1.53), hairdressers (1.28; 95% CI 1.18 to 1.40), seamen (1.22; 95% CI 1.16 to 1.30), printers (1.21; 95% CI 1.14 to 1.30), and plumbers (1.20; 95% CI 1.13 to 1.30). A significantly decreased risk of bladder cancer was observed among gardeners (0.78, 0.75 to 0.80), forestry workers (0.74; 95% CI 0.70 to 0.78), and farmers (0.70; 95% CI 0.68 to 0.71).

CONCLUSIONS

The SIR of bladder cancer was overall similar across the Nordic countries. The study suggests that occupation is evidently associated with bladder cancer risk.

摘要

目的

本研究旨在描述北欧国家膀胱癌发病率按职业类别的变化情况。

方法

研究队列包括1500万30岁以上的个体，他们参与了1960年、1970年、1980/1981年和/或1990年的一次或多次人口普查。对53种职业类别估计了标准化发病率（SIR）。

结果

在烟草工人（1.57；95%置信区间[CI]1.24至1.96）、烟囱清扫工（1.48；95%CI 1.21至1.80）、服务员（1.43；95%CI 1.33至1.53）、美发师（1.28；95%CI 1.18至1.40）、海员（1.22；95%CI 1.16至1.30）、印刷工（1.21；95%CI 1.14至1.30）和水管工（1.20；95%CI 1.13至1.30）中观察到SIR显著升高。在园艺工人（0.78，0.75至0.80）、林业工人（0.74；95%CI 0.70至0.78）和农民（0.70；95%CI 0.68至0.71）中观察到膀胱癌风险显著降低。