使用逆转录病毒载体将基因导入小鼠干细胞和小鼠体内。 - Suppr

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Gene transfer into murine stem cells and mice using retroviral vectors.

作者信息

Wagner E F, Keller G, Gilboa E, Rüther U, Stewart C

出版信息

Cold Spring Harb Symp Quant Biol. 1985;50:691-700. doi: 10.1101/sqb.1985.050.01.085.

DOI:10.1101/sqb.1985.050.01.085

PMID:3868504

Abstract

摘要

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Gene transfer into murine stem cells and mice using retroviral vectors.使用逆转录病毒载体将基因导入小鼠干细胞和小鼠体内。

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The ability of EK cells to form chimeras after selection of clones in G418 and some observations on the integration of retroviral vector proviral DNA into EK cells.在G418中筛选克隆后EK细胞形成嵌合体的能力以及关于逆转录病毒载体前病毒DNA整合到EK细胞中的一些观察结果。

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Introduction of genes into embryonal carcinoma cells and preimplantation embryos by retroviral vectors.通过逆转录病毒载体将基因导入胚胎癌细胞和植入前胚胎。

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Gene transfer into murine hematopoietic stem cells and bone marrow stromal cells.基因导入小鼠造血干细胞和骨髓基质细胞。

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Handicapped retroviral vectors efficiently transduce foreign genes into hematopoietic stem cells.缺陷逆转录病毒载体能有效地将外源基因转导至造血干细胞中。

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Retroviral transduction of murine and human hematopoietic progenitors and stem cells.鼠类和人类造血祖细胞及干细胞的逆转录病毒转导

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引用本文的文献

Germ-line transformation of mice.小鼠的种系转化

Annu Rev Genet. 1986;20:465-99. doi: 10.1146/annurev.ge.20.120186.002341.

Expression of retroviral vectors in transgenic mice obtained by embryo infection.通过胚胎感染获得的转基因小鼠中逆转录病毒载体的表达。

EMBO J. 1987 Feb;6(2):383-8. doi: 10.1002/j.1460-2075.1987.tb04766.x.

Deletions in a recombinant retrovirus genome associated with its expression in embryonal carcinoma cells.与重组逆转录病毒基因组在胚胎癌细胞中的表达相关的缺失。

J Virol. 1989 Oct;63(10):4431-3. doi: 10.1128/JVI.63.10.4431-4433.1989.

Embryonic stem cell virus, a recombinant murine retrovirus with expression in embryonic stem cells.胚胎干细胞病毒，一种在胚胎干细胞中表达的重组鼠逆转录病毒。

Proc Natl Acad Sci U S A. 1990 Dec;87(23):9202-6. doi: 10.1073/pnas.87.23.9202.

EMBO medal review. On transferring genes into stem cells and mice.欧洲分子生物学组织奖章综述。关于将基因导入干细胞和小鼠的研究。

EMBO J. 1990 Oct;9(10):3024-32. doi: 10.1002/j.1460-2075.1990.tb07498.x.

FVB/N: an inbred mouse strain preferable for transgenic analyses.FVB/N：一种适用于转基因分析的近交系小鼠品系。

Proc Natl Acad Sci U S A. 1991 Mar 15;88(6):2065-9. doi: 10.1073/pnas.88.6.2065.

Uterine expression of leukemia inhibitory factor coincides with the onset of blastocyst implantation.白血病抑制因子的子宫表达与胚泡着床的开始时间一致。

Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11408-12. doi: 10.1073/pnas.88.24.11408.

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