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美国医学生对医学研究中利益冲突的态度:一项调查

Attitudes Towards Conflicts of Interest in Medical Research: A Survey of US Medical Students.

作者信息

Takata Edmund T, Eschert John, Stafford Kerri, Alejo Andrew, Yu Angela S, Saffer Ryan, Shaikhly Marianna, Luong Lucas, O'Connor Cameron, Motupally Saagar, Staff Ilene, Walker Aseel, Finkel Kevin J

机构信息

New York Institute of Technology College of Osteopathic Medicine, Old Westbury, NY USA.

Integrated Anesthesia Associates, Hartford Hospital, Hartford, CT USA.

出版信息

Med Sci Educ. 2024 Feb 21;34(2):429-437. doi: 10.1007/s40670-024-02002-2. eCollection 2024 Apr.

Abstract

Industry funds nearly two-thirds of US healthcare research, and industry-sponsorship may produce more favorable research results and conclusions. Medical students report feeling inadequately prepared to avoid negative industry influence. Research of educational interventions that educate students on the potential effects of industry influence is lacking, and no interventions have demonstrated long-term benefit. Surveying and assessing student opinions of the relationship between industry and research may help improve future educational interventions. We surveyed preclinical and clinical students at seven US medical schools regarding their attitudes towards industry conflicts of interest (COIs) in medical research. A total of 466 medical students including 232 preclinical and 234 clinical students completed the survey. Of those who had research experience, clinical students were more likely than preclinical students to look for COIs (62.0% v 45.9%,  = .014) and to consider whether author COIs are pertinent to the article (68.1% v 54.1%,  = .023). Many disagreed that they felt adequately educated on the issue of COIs (42.7%), but most agreed that medical school should take a role in guiding student interactions with industry (65.0%). Students responded that all listed financial relationships between industry and investigator, except for providing food and/or beverage, would likely bias the investigator's research. Many students feel inadequately educated on industry issues in biomedical research, and most believe medical schools should help guide interactions with industry. Our findings support further development of educational interventions that prepare students to navigate the relationship between industry and medical research during and after medical school.

摘要

美国医疗保健研究近三分之二的资金来自行业,行业资助可能会产生更有利的研究结果和结论。医学生表示,他们觉得自己在避免行业负面影响方面准备不足。目前缺乏对学生进行行业影响潜在效应教育的干预措施研究,且尚无干预措施显示出长期益处。调查和评估学生对行业与研究关系的看法,可能有助于改进未来的教育干预措施。我们对美国7所医学院的临床前和临床学生就他们对医学研究中行业利益冲突(COI)的态度进行了调查。共有466名医学生完成了调查,其中包括232名临床前学生和234名临床学生。在有研究经验的学生中,临床学生比临床前学生更有可能查找利益冲突(62.0%对45.9%,P = 0.014),并考虑作者的利益冲突是否与文章相关(68.1%对54.1%,P = 0.023)。许多人不同意他们在利益冲突问题上受到了充分的教育(42.7%),但大多数人同意医学院应该在指导学生与行业的互动中发挥作用(65.0%)。学生们回应称,行业与研究者之间列出的所有财务关系,除了提供食品和/或饮料外,都可能使研究者的研究产生偏差。许多学生觉得自己在生物医学研究中的行业问题方面没有受到充分的教育,并且大多数人认为医学院应该帮助指导与行业的互动。我们的研究结果支持进一步开发教育干预措施,使学生在医学院期间及毕业后能够应对行业与医学研究之间的关系。

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