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体外受精(IVF)后孕期新冠病毒 2019 相关急性呼吸窘迫综合征(ARDS)的管理

Management of COVID-19-Associated Acute Respiratory Distress Syndrome (ARDS) During Pregnancy Following In Vitro Fertilization (IVF).

作者信息

Vashakidze Nika, Mateshvili Ana, Pachkoria Elene, Ratiani Levan

机构信息

Faculty of Medicine, Tbilisi State Medical University, Tbilisi, GEO.

Department of Infectious Diseases, The First University Clinic of Tbilisi State Medical University, Tbilisi, GEO.

出版信息

Cureus. 2024 Mar 29;16(3):e57223. doi: 10.7759/cureus.57223. eCollection 2024 Mar.

Abstract

Coronavirus disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is recognized for its heterogeneous clinical presentation, complex pathophysiology, and broad spectrum of manifestations. Obstetric patients have been a subject of considerable interest due to their potential vulnerability to more severe infection and adverse pregnancy outcomes, exemplified by this report of a 43-year-old pregnant female with severe COVID-19 infection and respiratory complications. This case report aims to contribute to the existing scientific knowledge by presenting a detailed clinical profile of a patient with COVID-19 who achieved pregnancy through in vitro fertilization (IVF) and discussing the management and outcomes of the infection. The neonate's negative COVID-19 tests suggest no intrauterine transmission; prompt medical interventions, including mechanical ventilation and targeted antibiotic therapy, were implemented to stabilize her condition. Close collaboration among the multidisciplinary team and careful monitoring of vital functions and laboratory parameters were crucial in managing the patient's complex condition. Thus, this case highlights the importance of a comprehensive and multidisciplinary approach in managing severe COVID-19 cases in pregnancy, emphasizing the need for prompt recognition of complications and timely intervention.

摘要

2019冠状病毒病(COVID-19)是由新型严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的疾病,以其临床表现的异质性、复杂的病理生理学和广泛的表现而闻名。产科患者因其可能更容易受到更严重感染和不良妊娠结局的影响而备受关注,本报告中一名43岁患有严重COVID-19感染和呼吸并发症的孕妇就是例证。本病例报告旨在通过呈现一名通过体外受精(IVF)怀孕的COVID-19患者的详细临床资料,并讨论感染的管理和结局,为现有的科学知识做出贡献。新生儿的COVID-19检测呈阴性,表明没有宫内传播;实施了包括机械通气和靶向抗生素治疗在内的及时医疗干预措施,以稳定她的病情。多学科团队之间的密切合作以及对生命体征和实验室参数的仔细监测对于管理患者的复杂病情至关重要。因此,本病例突出了在管理妊娠期严重COVID-19病例时采用全面多学科方法的重要性,强调了及时识别并发症和及时干预的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d82/11056601/79463192202f/cureus-0016-00000057223-i01.jpg

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