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[一例耳腔毛发母细胞瘤病例及文献复习]

[A case of trichoblastoma of the auricular cavity and review of the literature].

作者信息

Li Xuexue, Wei Xudong, Li Shujuan, Wang Qianru, Pan Xin

机构信息

First Clinical College of Medicine,Lanzhou University,Lanzhou,730000,China.

Department of Otolaryngology,Head and Neck Surgery,Gansu Provincial People's Hospital.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 May;38(5):448-452. doi: 10.13201/j.issn.2096-7993.2024.05.019.

Abstract

Trichoblastoma(TB) is a rare germ cell skin adnexal tumor of the hair, and it is a rare follicular tumor of the skin that differentiates from the hair germ epithelium and is often regarded as a benign skin tumorHowever, it is poorly confined and has a local infiltrative growth pattern. tb occurs in the head and neck region, especially in the face, and presents clinically as a slow growing, well-defined and elevated nodule. TB is routinely treated surgically. Due to the lack of universally accepted treatment guidelines or protocols, the recurrence rate after surgery is high, which makes clinical cure more difficult. In this study, a 65-year-old female patient was found to have a swelling with recurrent rupture and pus flow from the right external auditory canal opening and the auricular cavity. After initial misdiagnosis as otitis externa, she was treated with conventional anti-infective therapy, but her symptoms did not resolve and gradually worsened before coming to our hospital. The condition presented in this case is relativelyrare,therepre,timely and accurate diagnosis and treatment are crucial for prognosis improvement of such diseases.

摘要

毛母细胞瘤(TB)是一种罕见的起源于毛囊的生殖细胞皮肤附属器肿瘤,是一种罕见的皮肤毛囊肿瘤,由毛胚上皮分化而来,通常被视为良性皮肤肿瘤。然而,它边界不清,呈局部浸润性生长模式。TB发生于头颈部区域,尤其是面部,临床上表现为生长缓慢、边界清晰且隆起的结节。TB通常采用手术治疗。由于缺乏普遍接受的治疗指南或方案,术后复发率很高,这使得临床治愈更加困难。在本研究中,一名65岁女性患者被发现右外耳道开口及耳腔内有肿胀,反复破溃流脓。最初被误诊为外耳道炎,接受了常规抗感染治疗,但症状未缓解且逐渐加重,后来到我院就诊。本病例所呈现的病情相对罕见,因此,及时准确的诊断和治疗对于改善此类疾病的预后至关重要。

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本文引用的文献

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J Cutan Pathol. 2023 Jul;50(7):674-680. doi: 10.1111/cup.14389. Epub 2023 Feb 9.
3
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4
Trichoblastoma in reflectance confocal microscopy.
Australas J Dermatol. 2023 Feb;64(1):e89-e90. doi: 10.1111/ajd.13970. Epub 2022 Dec 24.
6
CD133, but Not CD44, May Serve as a Novel Biomarker for Differential Diagnosis Between Basal Cell Carcinoma and Trichoblastomas.
Clin Cosmet Investig Dermatol. 2022 Aug 2;15:1517-1526. doi: 10.2147/CCID.S373331. eCollection 2022.
7
[Giant nodule and keratinized facial basal cell carcinoma: a case report].
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9
Recurrent FOXK1::GRHL and GPS2::GRHL fusions in trichogerminoma.
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10
Trichoblastoma: A Consecutive Series of 349 Sporadic Cases Analyzed by Ackerman Subtypes.
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