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在用于黑色素瘤的氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描(FDG PET/CT)成像中偶然发现的子宫内膜癌。

Incidental endometrial cancer detected on FDG PET/CT imaging for melanoma.

作者信息

Kim Alex, Koshevarova Victoria, Mohammadinejad Payam, Murphy Micah, Bhargava Peeyush

机构信息

Department of Radiology, University of Texas Medical Branch, Galveston, TX.

出版信息

Radiol Case Rep. 2024 Apr 24;19(7):2845-2848. doi: 10.1016/j.radcr.2024.03.058. eCollection 2024 Jul.

DOI:10.1016/j.radcr.2024.03.058
PMID:38689809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11059307/
Abstract

This case report follows a 66-year-old female who originally presented with malignant melanoma in the left knee and recurrence in the left inguinal region. This prompted a whole body FDG PET/CT scan which showed incidental focal hypermetabolism in the uterus. The diagnosis of endometrial cancer was confirmed at biopsy, and the patient was treated with total abdominal hysterectomy. Melanoma patients are at increased risk of second primary malignancy, and endometrial cancer is a common second primary often diagnosed in cancer survivors. Incidental endometrial focal hypermetabolism should be investigated further for a synchronous malignancy, especially in a post-menopausal woman.

摘要

本病例报告的患者为一名66岁女性,最初表现为左膝恶性黑色素瘤,后左腹股沟区复发。这促使其进行了全身FDG PET/CT扫描,结果显示子宫内有偶然的局灶性代谢亢进。活检确诊为子宫内膜癌,患者接受了全腹子宫切除术。黑色素瘤患者发生第二原发性恶性肿瘤的风险增加,子宫内膜癌是癌症幸存者中常见的第二原发性肿瘤。对于偶然发现的子宫内膜局灶性代谢亢进,应进一步检查是否存在同步恶性肿瘤,尤其是在绝经后女性中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1563/11059307/cb3946032930/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1563/11059307/cb3946032930/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1563/11059307/cb3946032930/gr1.jpg

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Semin Nucl Med. 2024 Mar;54(2):270-292. doi: 10.1053/j.semnuclmed.2024.01.003. Epub 2024 Feb 11.
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18F-FDG PET/MRI and 18F-FDG PET/CT for the Management of Gynecological Malignancies: A Comprehensive Review of the Literature.18F-FDG PET/MRI与18F-FDG PET/CT在妇科恶性肿瘤管理中的应用:文献综述
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A Comparison of Dynamic Contrast-Enhanced Magnetic Resonance Imaging and T2-Weighted Imaging in Determining the Depth of Myometrial Invasion in Endometrial Carcinoma-A Retrospective Study.
动态对比增强磁共振成像与T2加权成像在确定子宫内膜癌肌层浸润深度中的比较——一项回顾性研究
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PET-CT in Clinical Adult Oncology-IV. Gynecologic and Genitourinary Malignancies.临床成人肿瘤学中的PET-CT-IV. 妇科和泌尿生殖系统恶性肿瘤
Cancers (Basel). 2022 Jun 18;14(12):3000. doi: 10.3390/cancers14123000.
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Survival for endometrial cancer as a second primary malignancy.子宫内膜癌作为第二原发恶性肿瘤的生存情况。
Cancer Med. 2022 Mar;11(6):1490-1501. doi: 10.1002/cam4.4554. Epub 2022 Jan 30.
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FDG-PET for Assessment of Endometrial and Vulvar Cancer.FDG-PET 用于评估子宫内膜和外阴癌。
Semin Nucl Med. 2019 Nov;49(6):471-483. doi: 10.1053/j.semnuclmed.2019.06.011. Epub 2019 Jul 3.
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Insights Imaging. 2019 Feb 13;10(1):19. doi: 10.1186/s13244-019-0696-8.
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Am Fam Physician. 2016 Mar 15;93(6):468-74.
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High Diagnostic Value of 18F-FDG PET/CT in Endometrial Cancer: Systematic Review and Meta-Analysis of the Literature.18F-FDG PET/CT在子宫内膜癌中的高诊断价值:文献系统评价与Meta分析
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