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患者特异性β-磷酸三钙支架用于定制化牙槽嵴增高:一例报告:病例报告:用于牙槽嵴 CBR 的患者特异性β-TCP 支架。

Patient-specific beta-tricalcium phosphate scaffold for customized alveolar ridge augmentation: a case report : Case Report: patient-specific β-TCP scaffold for alveolar ridge CBR.

机构信息

Department of Oral and Maxillofacial Surgery, University Hospital Basel, Spitalstrasse 21, Basel, 4031, Switzerland.

Department of Oral and Maxillofacial Surgery, University Hospital Zurich, Frauenklinikstrasse 24, Zurich, 8091, Switzerland.

出版信息

Int J Implant Dent. 2024 May 1;10(1):21. doi: 10.1186/s40729-024-00541-2.

Abstract

BACKGROUND

Beta-tricalcium phosphate (β-TCP) is a biocompatible ceramic material widely used in the field of oral regeneration. Due to its excellent biological and mechanical properties, it is increasingly utilized for alveolar ridge augmentation or guided bone regeneration (GBR). With recent advances in computer-aided design and manufacturing (CAD/CAM), β-TCP can now be used in the form of digitally designed patient-specific scaffolds for customized bone regeneration (CBR) of advanced defects in a two-stage implant therapy concept. In this case report following the CARE case report guidelines, we present a novel application of a patient-specific β-TCP scaffold in pre-implant mandibular alveolar ridge augmentation.

CASE PRESENTATION

A 63-year-old female patient with significant horizontal bone loss in the posterior mandible was treated with a custom β-TCP scaffold in the context of a two-stage backward-planned implant therapy. Cone-beam computed tomography nine months after augmentation showed successful integration of the scaffold into the surrounding bone, allowing implant placement. Follow-up until two years after initial surgery showed excellent oral and peri-implant health.

CONCLUSIONS

This case highlights the potential of patient-specific β-TCP scaffolds for alveolar ridge augmentation and their advantage over traditional techniques, including avoidance of xeno-, allo-, and autografts. The results provide encouraging evidence for their use in clinical practice. Patient-specific β-TCP scaffolds may be a promising alternative for clinicians seeking to provide their patients with safe, predictable, and effective alveolar ridge augmentation results in customized bone regeneration procedures.

摘要

背景

β-磷酸三钙(β-TCP)是一种生物相容性陶瓷材料,广泛应用于口腔再生领域。由于其优异的生物和机械性能,它越来越多地用于牙槽嵴增量或引导骨再生(GBR)。随着计算机辅助设计和制造(CAD/CAM)的最新进展,β-TCP 现在可以以数字化设计的患者特异性支架的形式用于两阶段种植体治疗概念中高级缺损的定制骨再生(CBR)。在遵循 CARE 病例报告指南的情况下,本病例报告介绍了一种新型的患者特异性β-TCP 支架在种植前下颌牙槽嵴增量中的应用。

病例介绍

一名 63 岁女性患者,下颌后牙有明显的水平骨缺失,采用定制β-TCP 支架进行两阶段后退式种植体治疗。增强后九个月的锥形束计算机断层扫描显示支架成功整合到周围骨骼中,允许植入物放置。初始手术后两年的随访显示口腔和种植体周围健康状况良好。

结论

本病例强调了患者特异性β-TCP 支架在牙槽嵴增量中的潜力及其优于传统技术的优势,包括避免使用异种、同种和自体移植物。结果为其在临床实践中的应用提供了令人鼓舞的证据。对于寻求为患者提供安全、可预测和有效的牙槽嵴增量结果的临床医生来说,患者特异性β-TCP 支架可能是一种有前途的替代方案,用于定制骨再生手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a36d/11063008/be8db2c238d0/40729_2024_541_Fig1_HTML.jpg

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