Khan Mohd J, Tauheed Nazia, Siddiqui Anwar H, Sabir Amir B, Haleem Shahla
Department of Anaesthesiology and Critical Care, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, IND.
Department of Physiology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, IND.
Cureus. 2024 Apr 1;16(4):e57408. doi: 10.7759/cureus.57408. eCollection 2024 Apr.
Total knee arthroplasty (TKA) is a common surgical procedure for patients with knee osteoarthritis, often associated with postoperative pain. Effective pain management strategies are essential for improving patient outcomes and satisfaction. This study aimed to compare the efficacy of two analgesic modalities, local infiltration analgesia (LIA) and adductor canal block (ACB), in providing postoperative pain relief for patients undergoing TKA.
This prospective randomized comparative study included 60 patients undergoing TKA for knee osteoarthritis under subarachnoid block (spinal anaesthesia). Patients were divided into two groups: LIA group (local wound infiltration with periarticular injection of bupivacaine 0.125% + dexmedetomidine 1 mcg/kg) and ACB group (ACB with bupivacaine 0.125% + 1 mcg/kg dexmedetomidine). Pain relief was assessed using the Numerical Rating Scale (NRS) score, time to first rescue analgesic requirement (NRS > 3), and total amount of analgesic needed in the first 24 hours post-surgery.
The time to first perception of pain with NRS > 3 was 11.30±0.8 hours in the ACB group and 9.40 ± 1.1 hours in the LIA group, with a statistically significant difference (p < 0.001). Additionally, the total number of rescue analgesic doses given in the first 24 hours post-operatively differed significantly between the two groups (p = 0.046).
The study concludes that ACB is an effective postoperative analgesic modality, superior to local infiltration analgesia, for patients undergoing TKA.
全膝关节置换术(TKA)是膝骨关节炎患者常见的外科手术,术后常伴有疼痛。有效的疼痛管理策略对于改善患者预后和满意度至关重要。本研究旨在比较两种镇痛方式,即局部浸润镇痛(LIA)和收肌管阻滞(ACB),为接受TKA手术的患者提供术后疼痛缓解的效果。
这项前瞻性随机对照研究纳入了60例在蛛网膜下腔阻滞(脊髓麻醉)下接受TKA治疗膝骨关节炎的患者。患者分为两组:LIA组(局部伤口浸润联合关节周围注射0.125%布比卡因+1μg/kg右美托咪定)和ACB组(ACB联合0.125%布比卡因+1μg/kg右美托咪定)。使用数字评分量表(NRS)评分、首次需要补救性镇痛的时间(NRS>3)以及术后24小时内所需的镇痛总量来评估疼痛缓解情况。
ACB组NRS>3时首次感觉到疼痛的时间为11.30±0.8小时,LIA组为9.40±1.1小时,差异有统计学意义(p<0.001)。此外,两组术后24小时内给予的补救性镇痛剂量总数差异有统计学意义(p=0.046)。
该研究得出结论,对于接受TKA手术的患者,ACB是一种有效的术后镇痛方式,优于局部浸润镇痛。