Division of Endocrinology Metabolism and Diabetes, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.
Anschutz Health and Wellness Center, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.
J Appl Physiol (1985). 2024 Jul 1;137(1):1-9. doi: 10.1152/japplphysiol.00763.2023. Epub 2024 May 2.
We tested whether spontaneous physical activity (SPA) from accelerometers could be used in a whole room calorimeter to estimate thermic effect of food (TEF). Eleven healthy participants ( = 7 females; age: 27 ± 4 yr; body mass index: 22.8 ± 2.6 kg/m) completed two 23-h visits in randomized order: one "fed" with meals provided and one "fasted" with no food. SPA was measured by ActivPAL and Actigraph accelerometers. Criterion TEF was calculated as the difference in total daily energy expenditure (TDEE) between fed and fasted visits and compared with three methods of estimating TEF: ) SPA-adjusted TEF (adjTEF)-difference in TDEE without SPA between visits, ) Wakeful TEF-difference in energy expenditure obtained from linear regression and basal metabolic rate during waking hours, ) 24-h TEF-increase in TDEE above SPA and sleeping metabolic rate. Criterion TEF was 9.4 ± 4.5% of TDEE. AdjTEF (difference in estimated vs. criterion TEF: activPAL: -0.3 ± 3.3%; Actigraph: -1.8 ± 8.0%) and wakeful TEF (activPAL: -0.9 ± 6.1%; Actigraph: -2.8 ± 7.6%) derived from both accelerometers did not differ from criterion TEF (all > 0.05). ActivPAL-derived 24-h TEF overestimated TEF (6.8 ± 5.4%, = 0.002), whereas Actigraph-derived 24-h TEF was not significantly different (4.3 ± 9.4%, = 0.156). TEF estimations using activPAL tended to show better individual-level agreement (i.e., smaller coefficients of variation). Both accelerometers can be used to estimate TEF in a whole room calorimeter; wakeful TEF using activPAL is the most viable option given strong group-level accuracy and reasonable individual agreement. Two research-grade accelerometers can effectively estimate spontaneous physical activity and improve the estimation of thermic effect of food (TEF) in whole room calorimeters. The activPAL demonstrates strong group-level accuracy and reasonable individual-level agreement in estimating wakeful TEF, whereas a hip-worn Actigraph is an acceptable approach for estimating 24-h TEF. These results highlight the promising potential of accelerometers in advancing energy balance research by improving the assessment of TEF within whole room calorimeters.
我们测试了加速度计记录的自发性体力活动（SPA）是否可用于整个房间量热计来估计食物的热效应（TEF）。11 名健康参与者（= 7 名女性；年龄：27 ± 4 岁；体重指数：22.8 ± 2.6 kg/m）以随机顺序完成了两次 23 小时的访问：一次是“进食”，提供膳食，一次是“禁食”，没有食物。SPA 通过 ActivPAL 和 Actigraph 加速度计进行测量。标准 TEF 计算为进食和禁食访问之间总每日能量消耗（TDEE）的差异，并与三种估计 TEF 的方法进行比较：）SPA 调整 TEF（adjTEF）-访问之间没有 SPA 的 TDEE 差异，）清醒 TEF-线性回归和清醒期间基础代谢率获得的能量消耗差异，）24 小时 TEF-SPA 和睡眠代谢率以上的 TDEE 增加。标准 TEF 为 TDEE 的 9.4 ± 4.5%。来自两个加速度计的 adjTEF（估计与标准 TEF 的差异：activPAL：-0.3 ± 3.3%；Actigraph：-1.8 ± 8.0%）和清醒 TEF（activPAL：-0.9 ± 6.1%；Actigraph：-2.8 ± 7.6%）与标准 TEF 无差异（均> 0.05）。来自 ActivPAL 的 24 小时 TEF 高估了 TEF（6.8 ± 5.4%，= 0.002），而 Actigraph 衍生的 24 小时 TEF 则无显著差异（4.3 ± 9.4%，= 0.156）。使用 activPAL 的 TEF 估计倾向于显示更好的个体水平一致性（即，较小的变异系数）。两个加速度计都可用于整个房间量热计中 TEF 的估计；鉴于强烈的组水平准确性和合理的个体一致性，使用 activPAL 的清醒 TEF 是最可行的选择。两种研究级加速度计可有效估计自发性体力活动并提高整个房间量热计中食物热效应（TEF）的估计值。activPAL 在估计清醒 TEF 方面具有很强的组水平准确性和合理的个体水平一致性，而 hip-worn Actigraph 则是估计 24 小时 TEF 的可接受方法。这些结果突出了加速度计在通过改善整个房间量热计中 TEF 的评估来推进能量平衡研究方面的有前途的潜力。
