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2 例猫假性醛固酮增多症和获得性肾性醛固酮抵抗伴高钾型 IV 型肾小管性酸中毒

Pseudohypoaldosteronism and acquired renal aldosterone resistance with hyperkalemic type IV renal tubular acidosis in 2 cats.

机构信息

Small Animal Veterinary Specialists, Wyndmoor, Pennsylvania, USA.

Friendship Hospital for Animals, Washington, District of Columbia, USA.

出版信息

J Vet Intern Med. 2024 Jul-Aug;38(4):2344-2347. doi: 10.1111/jvim.17098. Epub 2024 May 2.

DOI:10.1111/jvim.17098
PMID:38695414
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11256122/
Abstract

This report describes the diagnosis and treatment of aldosterone resistance (AR) and acquired hyperkalemic type IV renal tubular acidosis (RTA) in 2 cats comparable to acquired pseudohypoaldosteronism in people. One cat developed AR from chronic kidney disease after an acute kidney injury and was treated with furosemide per os, which resolved the hyperkalemic RTA. The second cat developed transient AR secondary to a bacterial urinary tract infection associated with urethral catheterization, and treatment with antibiotics resolved the hyperkalemic RTA.

摘要

本报告描述了 2 只类似于人类获得性假性低醛固酮血症的猫的醛固酮抵抗 (AR) 和获得性高钾性 IV 型肾小管酸中毒 (RTA) 的诊断和治疗。一只猫在急性肾损伤后因慢性肾病而发生 AR，并接受了口服呋塞米治疗，高钾性 RTA 得到解决。第二只猫继发于与尿道置管相关的细菌尿路感染的短暂性 AR，抗生素治疗解决了高钾性 RTA。

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Pseudohypoaldosteronism and acquired renal aldosterone resistance with hyperkalemic type IV renal tubular acidosis in 2 cats.
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