联合缺失多功能 MGF505-7R 和 H240R 基因可产生安全有效的非洲猪瘟病毒减毒活疫苗候选株。
Joint deletion of multifunctional MGF505-7R and H240R genes generates a safe and effective African swine fever virus attenuated live vaccine candidate.
机构信息
Division of Fundamental Immunology, National African Swine Fever Para-reference Laboratory, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, China; Heilongjiang Provincial Key Laboratory of Veterinary Immunology, Harbin 150069, China.
Division of Fundamental Immunology, National African Swine Fever Para-reference Laboratory, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, China; Heilongjiang Provincial Key Laboratory of Veterinary Immunology, Harbin 150069, China.
出版信息
Virol Sin. 2024 Jun;39(3):355-357. doi: 10.1016/j.virs.2024.04.007. Epub 2024 Apr 30.
• and are virulence-related genes. • ASFV-ΔΔ is attenuated. • The candidate vaccine is safe and protective.
• 和 是与毒力相关的基因。• ASFV-ΔΔ 是减毒的。• 候选疫苗是安全和有效的。
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