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简要且最新的甲壳动物神经内分泌系统介绍。

A brief and updated introduction to the neuroendocrine system of crustaceans.

机构信息

Comparative Metabolism and Endocrinology Laboratory (LAMEC), Post Graduation Program in Biological Sciences, Porto Alegre, RS, Brazil; Department of Physiology, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.

Institute of Marine and Environmental Technology (IMET), University of Maryland Center for Environmental Sciences (UMCES), Baltimore, MD, USA.

出版信息

Mol Cell Endocrinol. 2024 Sep 1;590:112265. doi: 10.1016/j.mce.2024.112265. Epub 2024 May 1.

Abstract

The neuroendocrine system of crustaceans is complex and regulates many processes, such as development, growth, reproduction, osmoregulation, behavior, and metabolism. Once stimulated, crustaceans' neuroendocrine tissues modulate the release of monoamines, ecdysteroids, and neuropeptides that can act as hormones or neurotransmitters. Over a few decades, research has unraveled some mechanisms governing these processes, substantially contributing to understanding crustacean physiology. More aspects of crustacean neuroendocrinology are being comprehended with molecular biology, transcriptome, and genomics analyses. Hence, these studies will also significantly enhance the ability to cultivate decapods, such as crabs and shrimps, used as human food sources. In this review, current knowledge on crustacean endocrinology is updated with new findings about crustacean hormones, focusing mainly on the main neuroendocrine organs and their hormones and the effects of these molecules regulating metabolism, growth, reproduction, and color adaptation. New evidence about vertebrate-type hormones found in crustaceans is included and discussed. Finally, this review may assist in understanding how the emerging chemicals of environmental concern can potentially impair and disrupt crustacean's endocrine functions and their physiology.

摘要

甲壳动物的神经内分泌系统复杂,调节着许多过程,如发育、生长、繁殖、渗透调节、行为和代谢。甲壳动物的神经内分泌组织一旦受到刺激,就会调节单胺类、蜕皮激素和神经肽的释放,这些物质可以作为激素或神经递质发挥作用。几十年来,研究已经揭示了一些控制这些过程的机制,这对理解甲壳动物生理学有很大的贡献。随着分子生物学、转录组和基因组学分析的开展,甲壳动物神经内分泌学的更多方面正在被理解。因此,这些研究也将显著提高养殖十足目动物(如蟹和虾)的能力,这些动物被用作人类的食物来源。在这篇综述中,更新了甲壳动物内分泌学的现有知识,并介绍了关于甲壳动物激素的新发现,主要集中在主要的神经内分泌器官及其激素,以及这些调节代谢、生长、繁殖和颜色适应的分子的作用。还包括并讨论了在甲壳动物中发现的脊椎动物型激素的新证据。最后,这篇综述可能有助于理解环境关注的新兴化学物质如何可能损害和扰乱甲壳动物的内分泌功能及其生理学。

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