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低压低氧对蟾蜍精子发生、睾丸间质细胞及δ5-3β-羟基类固醇脱氢酶活性的影响

Effect of hypobaric hypoxia on spermatogenesis, Leydig cells and delta 5-3 beta-hydroxysteroid dehydrogenase activity in toad.

作者信息

Biswas H M, Boral M C, Ghosh A K

出版信息

Indian J Physiol Pharmacol. 1985 Jul-Sep;29(3):139-45.

PMID:3869809
Abstract

The effect of different grades of hypobaric hypoxia for 48 hours was studied on spermatogenesis, Leydig cells and delta 5-3 beta-hydroxysteroid dehydrogenase activity in toad (Bufo melanostictus). Maximum inhibition of testicular activity was noted in 7,315 m exposed animals. The impairment of testicular function at high altitude is possibly due to inhibition of gonadotrophin secretion.

摘要

研究了不同程度的低压缺氧持续48小时对蟾蜍(黑眶蟾蜍)精子发生、睾丸间质细胞和δ5-3β-羟基类固醇脱氢酶活性的影响。在暴露于7315米高度的动物中观察到睾丸活动受到最大抑制。高海拔地区睾丸功能受损可能是由于促性腺激素分泌受到抑制。

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