病例报告及文献综述：一名3岁女童的无症状性沿岸细胞血管瘤
Case report and literature review: Asymptomatic littoral cell angioma in a 3-year-old girl.
作者信息
Mou Yanling, Yang Liucheng, Wang Jianjun, Chen Qinming, Zhang Mengzhen, Zhang Xi, Tan Rongying, Adam Mahamat Djibril, Wu Kai
机构信息
Department of Pediatric Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
出版信息
Front Pediatr. 2024 Apr 18;12:1383015. doi: 10.3389/fped.2024.1383015. eCollection 2024.
BACKGROUND
Littoral cell angioma (LCA) is an extremely uncommon benign vascular tumor of the spleen. Cases of LCA in infants are rarely reported, and due to the rarity of the tumor and non-specific symptoms, the diagnosis of LCA is often overlooked in clinical practice.
CASE REPORT
We present a 3-year-old girl with pulmonary inflammation who was admitted to the hospital due to the discovery of a space-occupying lesion in the spleen. Pathology after splenectomy confirmed LCA, and there was no recurrence observed at the 5-month follow-up examination.
CONCLUSION
LCA should be considered when a child shows asymptomatic splenomegaly, with antigen expression indicating dual positivity of endothelial and histiocytic markers. Laparoscopic splenectomy remains the primary method of treating LCA.
背景
脾 littoral 细胞血管瘤（LCA）是一种极为罕见的脾脏良性血管肿瘤。婴儿 LCA 病例鲜有报道，由于该肿瘤罕见且症状不具特异性，在临床实践中 LCA 的诊断常被忽视。
病例报告
我们报告一例 3 岁患肺炎女童，因脾脏发现占位性病变入院。脾切除术后病理证实为 LCA，5 个月随访检查未观察到复发。
结论
当儿童出现无症状脾肿大且抗原表达显示内皮和组织细胞标志物双阳性时，应考虑 LCA。腹腔镜脾切除术仍是治疗 LCA 的主要方法。
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