Ling L H
Zhonghua Zhong Liu Za Zhi. 1985 Nov;7(6):423-5.
Cells of mice MA-737 mammary adenocarcinoma from 5 different generations were analysed by G and C banding techniques. Altogether, 540 metaphase plates were studied. All chromosomes showed telocentric and C bands. The modal chromosome numbers were 41, 82, 86, 89 and 91. The karyotype of cells with 41 modal number was 41, XO, +7 +M. In most of the cells, one or two marker chromosomes were present. This marker is characteristic of all MA-737 cells. The relationship between chromosome aberration and malignant transformation is briefly discussed.
采用G带和C带技术分析了5个不同代数的小鼠MA-737乳腺腺癌细胞。总共研究了540个中期板。所有染色体均显示为端着丝粒染色体和C带。众数染色体数分别为41、82、86、89和91。众数为41的细胞的核型为41,XO,+7 +M。在大多数细胞中,存在一条或两条标记染色体。这种标记是所有MA-737细胞的特征。简要讨论了染色体畸变与恶性转化之间的关系。