Department of Economic and Administrative Pharmacy (EAP), Faculty of Pharmacy, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.
Faculty of Pharmaceutical Management and Economics, Hanoi University of Pharmacy, Hanoi, Vietnam.
Psychol Health Med. 2024 Sep;29(8):1448-1465. doi: 10.1080/13548506.2024.2342589. Epub 2024 May 3.
Antibiotic resistance (AR) rates in Vietnam are among the highest in Asia, and recent infections due to multi-drug resistance in the country have caused thousands of deaths each year. This study investigated a Vietnamese community's preferences for antibiotic treatment and its knowledge and attitudes regarding antibiotics. A discrete choice experiment-based survey was developed and administered to the population of interest. The respondents were given sociodemographic-, knowledge- and attitude-related items and 17 pairs of choice tasks. Two hypothetical options were included in each choice task. Latent class analysis was conducted to determine the differences among the respondents' preferences. Among 1,014 respondents, 805 (79.4%) gave valid questionnaires. A three-latent-class model with four covariates (age, healthcare-related education or career, occupation, and attitude classifications) was used in the analysis. All five attributes significantly influenced the respondents' decisions. The majority, including young employed respondents with non-healthcare-related work or education, found treatment failure more important. Older respondents who had healthcare-related education/careers and/or appropriate antibiotic use- and antibiotics resistance-related attitudes, regarded contribution to antibiotic resistance as an important attribute in selecting antibiotic treatments. Unemployed individuals with correct knowledge identified the cost of antibiotic treatment as the most essential decision-making factor. Findings suggest minimal antibiotic impact on resistance; only 7.83% view it as amajor concern. The respondents exhibited substantial preference heterogeneity, and the general Vietnamese public had poor knowledge of and attitudes toward antibiotic use and antibiotic resistance. This study emphasizes the need for individual responsibility for antibiotic resistance and appropriate antibiotic use.
越南的抗生素耐药率在亚洲属于最高之列，该国近年来因多重耐药性感染导致每年有数千人死亡。本研究调查了越南社区对抗生素治疗的偏好及其对抗生素的知识和态度。开发并向目标人群管理了一项基于离散选择实验的调查。向受访者提供了与社会人口统计学、知识和态度相关的项目以及 17 对选择任务。每个选择任务都包含两个假设选项。进行潜在类别分析以确定受访者偏好之间的差异。在 1014 名受访者中，有 805 名（79.4%）给出了有效的问卷。在分析中使用了包含四个协变量（年龄、与医疗保健相关的教育或职业、职业和态度分类）的三潜在类别模型。所有五个属性都显著影响了受访者的决策。大多数包括从事非医疗保健相关工作或教育的年轻在职受访者，认为治疗失败更重要。具有医疗保健相关教育/职业和/或适当的抗生素使用和抗生素耐药性相关态度的年长受访者，将对抗生素耐药性的贡献视为选择抗生素治疗的重要属性。具有正确知识的失业者将抗生素治疗成本视为最重要的决策因素。研究结果表明抗生素对抗生素耐药性的影响最小，只有 7.83%的人认为这是一个主要问题。受访者表现出显著的偏好异质性，越南公众普遍对抗生素的使用和抗生素耐药性的知识和态度较差。本研究强调了对抗生素耐药性采取个人责任和适当使用抗生素的必要性。
