Chen Cong, Liu Yang, Yang Songwei, Chen Ming, Liao Jing
College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China.
Institute of Innovation and Applied Research in Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China.
Medicine (Baltimore). 2024 May 3;103(18):e37969. doi: 10.1097/MD.0000000000037969.
Familial hypertrophic cardiomyopathy (FHCM) is an inherited cardiac disease caused by mutations of sarcomere proteins and can be the underlining substrate for major cardiovascular events. Early identification and diagnosis of FHCM are essential to reduce sudden cardiac death. So, this paper summarized the current knowledge on FHCM, and displayed the analysis via bibliometrics method. The relevant literature on FHCM were screened searched via the Web of Science Core Collection database from 2012 to 2022. The literatures were was summarized and analyzed via the bibliometrics method analyzed via CiteSpace and VOSviewer according to topic categories, distribution of spatiotemporal omics and authors, as well as references. Since 2012, there are 909 research articles and reviews related to FHCM. The number of publication for the past 10 years have shown that the development of FHCM research has been steady, with the largest amount of literature in 2012. The most published papers were from the United States, followed by the United Kingdom and Italy. The University of London (63 papers) was the institution that published the most research articles, followed by Harvard University (45 papers) and University College London (45 papers). Keywords formed 3 clusters, focused on the pathogenesis of FHCM, the diagnosis of FHCM, FHCM complications, respectively. The bibliometric analysis and visualization techniques employed herein highlight key trends and focal points in the field, predominantly centered around FHCM's pathogenesis, diagnostic approaches, and its complications. These insights are instrumental in steering future research directions in this area.
家族性肥厚型心肌病（FHCM）是一种由肌节蛋白突变引起的遗传性心脏病，可能是主要心血管事件的潜在基础。早期识别和诊断FHCM对于减少心源性猝死至关重要。因此，本文总结了关于FHCM的现有知识，并通过文献计量学方法进行了分析。通过Web of Science核心合集数据库检索2012年至2022年期间关于FHCM的相关文献。根据主题类别、时空组学分布、作者以及参考文献，使用CiteSpace和VOSviewer通过文献计量学方法对文献进行总结和分析。自2012年以来，有909篇与FHCM相关的研究文章和综述。过去10年的发表数量表明，FHCM研究发展稳定，2012年的文献数量最多。发表论文最多的国家是美国，其次是英国和意大利。伦敦大学（63篇论文）是发表研究文章最多的机构，其次是哈佛大学（45篇论文）和伦敦大学学院（45篇论文）。关键词形成了3个聚类，分别聚焦于FHCM的发病机制、FHCM的诊断、FHCM并发症。本文采用的文献计量分析和可视化技术突出了该领域的关键趋势和重点，主要围绕FHCM的发病机制、诊断方法及其并发症。这些见解有助于指导该领域未来的研究方向。
