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应对胃肠道挑战:镰状细胞贫血中的腹泻

Managing gastrointestinal challenges: Diarrhea in sickle cell anemia.

作者信息

Obeagu Emmanuel Ifeanyi, Obeagu Getrude Uzoma

机构信息

Department of Medical Laboratory Science, Kampala International University, Uganda.

School of Nursing Science, Kampala International University, Uganda.

出版信息

Medicine (Baltimore). 2024 May 3;103(18):e38075. doi: 10.1097/MD.0000000000038075.

Abstract

Sickle cell anemia (SCA), a hereditary hemoglobinopathy, is characterized by the presence of abnormal hemoglobin and has long been associated with a wide range of complications. While much attention has been given to the condition hematological aspects, gastrointestinal complications, particularly diarrhea, have been relatively understudied and often overlooked. This publication delves into the management of gastrointestinal challenges, with a focus on diarrhea, in individuals living with SCA. The pathophysiology of SCA is intrinsically linked to gastrointestinal complications, and diarrhea is a common manifestation of this condition. This abstract publication outlines the key elements discussed in the full-length work, which includes the clinical presentation of diarrhea in these patients, the diagnostic tools used to evaluate the condition, and various management strategies to alleviate symptoms and enhance the overall quality of life for affected individuals. The paper emphasizes the importance of patient education, offering healthcare professionals valuable insights into how to inform and support patients in managing their conditions effectively. It also highlights the need for continued research to further our understanding of gastrointestinal challenges in SCA and to identify potential areas for future therapeutic interventions. Ultimately, the comprehensive management of diarrhea in individuals with SCA is vital for their overall well-being. This publication serves as a valuable resource for healthcare providers, researchers, and caregivers in addressing the gastrointestinal challenges that accompany SCA, ultimately working toward a better quality of life for those affected by this condition.

摘要

镰状细胞贫血(SCA)是一种遗传性血红蛋白病,其特征是存在异常血红蛋白,长期以来一直与多种并发症相关。虽然人们对该疾病的血液学方面给予了很多关注,但胃肠道并发症,尤其是腹泻,相对研究不足且常常被忽视。本出版物深入探讨了SCA患者胃肠道问题的管理,重点关注腹泻。SCA的病理生理学与胃肠道并发症有着内在联系,腹泻是该疾病的常见表现。本摘要性出版物概述了全文讨论的关键内容,包括这些患者腹泻的临床表现、用于评估病情的诊断工具,以及缓解症状和提高受影响个体整体生活质量的各种管理策略。该论文强调了患者教育的重要性,为医护人员提供了关于如何有效地告知和支持患者管理病情的宝贵见解。它还强调了持续研究的必要性,以进一步了解SCA中的胃肠道问题,并确定未来治疗干预的潜在领域。最终,全面管理SCA患者的腹泻对他们的整体健康至关重要。本出版物为医护人员、研究人员和护理人员应对SCA伴随的胃肠道问题提供了宝贵资源,最终致力于改善受该疾病影响者的生活质量。

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