State Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, People's Republic of China.
ACS Appl Bio Mater. 2024 May 20;7(5):2695-2703. doi: 10.1021/acsabm.4c00376. Epub 2024 May 3.
Gold nanoclusters (AuNCs), with customized structures and diverse optical properties, are promising optical materials. Constructing composite systems by the assembly and incorporation of AuNCs can utilize their optical properties to achieve diagnostic and therapeutic applications in the biological field. Therefore, the exploration of the assembly behaviors of AuNCs and the enhancement of their performance has attracted widespread interest. In this review, we introduce multiple interactions and assembly modes that are prevalent in nanocomposites and microcomposites based on AuNCs. Then, the functions of AuNC composites for bioapplications are demonstrated in detail. These composite systems have inherited and enhanced the inherent optical performances of the AuNCs to meet diverse requirements for biological sensing and optical treatments. Finally, we discuss the prospects of AuNC composites and highlight the challenges and opportunities in biomedical applications.
金纳米簇（AuNCs）具有定制的结构和多样化的光学性质，是很有前途的光学材料。通过组装和掺入 AuNCs 构建复合体系，可以利用其光学性质在生物领域实现诊断和治疗应用。因此，探索 AuNCs 的组装行为并提高其性能引起了广泛的关注。在这篇综述中，我们介绍了基于 AuNCs 的纳米复合材料和微复合材料中常见的多种相互作用和组装模式。然后，详细展示了 AuNC 复合材料在生物应用中的功能。这些复合体系继承和增强了 AuNCs 的固有光学性能，以满足生物传感和光学处理的多样化要求。最后，我们讨论了 AuNC 复合材料的前景，并强调了其在生物医学应用中的挑战和机遇。
