Gualda Luz María González, Gonzalez-Rubio Jesus, Najera Alberto, Dies María Aliño, Cremades Rubén Roig, Espuña Javier Bajen, Alarcón Carmen Escobar, Sirvent Noelia Navarro, Lozano María Jesús Montes, Rodríguez Karen Nieto
Servicio de Salud de Castilla-La Mancha, Complejo Hospitalario Universitario de Albacete (CHUA), Albacete, Spain.
Department of Medical Sciences. Faculty of Medicine of Albacete, University of Castilla-La Mancha, School of Medicine, Calle Almansa 14, 02008, Albacete, Spain.
Soc Psychiatry Psychiatr Epidemiol. 2025 Feb;60(2):341-352. doi: 10.1007/s00127-024-02675-5. Epub 2024 May 3.
The functional-cognitive impact of first-episode psychosis (FEP) is extremely relevant and implies dysfunction from early life stages like adolescence and youth. Like other illnesses, FEP incidence is also influenced by environmental factors. It is necessary to attend to this age group with early interventions and to act on the environmental factors that the literature correlates with increased FEP incidence: socio-economic aspects, social adversity, bullying at school or cannabis use. In this context, identifying the areas of cities where FEP patients concentrate is important to perform early interventions. The spatial analysis of patient distribution in a whole city is one way to identify the most vulnerable areas and to propose psycho-social interventions for the possible prevention and/or early detection of FEP by improving urban mental health.
An epidemiological study of point patterns to determine the areas of a city with a higher incidence of patients with FEP. To do so, the addresses of FEP cases were georeferenced from 1 January 2016 to 31 October 2022, and 109 FEP patients were analysed. Data from a random sample of 383 controls, comprising their addresses, age, and sex, were randomly obtained from the official city council database. By GIS, the areas with higher FEP incidence were analysed to see if they coincided with the zones where inhabitants with lower incomes lived.
The risk ratio of the FEP patients was compatible with the constant risk ratio in Albacete (p = 0.22). When performing the process separately with cases and controls only in men and women, the results were not significant for both distributions (p value: 0.12 and 0.57, respectively). Nonetheless, areas within the city had a significantly higher risk. These groups of cases coincided with those who had lower income and more inequality for women, but this pattern was not clear for men.
Classifying city areas per income can help to determine the zones at higher risk of FEP, which would allow early healthcare and preventive measures for these zones.
首发精神病(FEP)的功能认知影响极为重要,意味着从青春期和青年期等生命早期阶段就出现功能障碍。与其他疾病一样,FEP的发病率也受环境因素影响。有必要对这一年龄组进行早期干预,并针对文献中与FEP发病率增加相关的环境因素采取行动:社会经济方面、社会逆境、校园欺凌或大麻使用。在此背景下,确定FEP患者集中的城市区域对于开展早期干预很重要。对整个城市患者分布进行空间分析是识别最脆弱区域并通过改善城市心理健康状况为FEP的可能预防和/或早期检测提出心理社会干预措施的一种方法。
一项点模式流行病学研究,以确定城市中FEP患者发病率较高的区域。为此,对2016年1月1日至2022年10月31日期间FEP病例的地址进行地理定位,并分析了109例FEP患者。从市议会官方数据库中随机获取383名对照的随机样本数据,包括他们的地址、年龄和性别。通过地理信息系统(GIS)分析FEP发病率较高的区域,看是否与低收入居民居住的区域重合。
FEP患者的风险比与阿尔巴塞特的恒定风险比相符(p = 0.22)。仅对男性和女性的病例与对照分别进行该过程时,两种分布的结果均不显著(p值分别为0.12和0.57)。尽管如此,城市内的区域风险显著更高。这些病例组与低收入且女性不平等程度更高的人群重合,但男性的这种模式不明显。
按收入对城市区域进行分类有助于确定FEP风险较高的区域,从而可为这些区域采取早期医疗保健和预防措施。