Servicio de Cardiología, Hospital Clínico Universitario Virgen de la Arrixaca, Ctra. Murcia-Cartagena s/n. 30120, Murcia, Spain.
Servicio de Cardiología, Hospital Universitario de Cabueñes, Gijón, Spain.
Curr Heart Fail Rep. 2024 Aug;21(4):354-366. doi: 10.1007/s11897-024-00663-z. Epub 2024 May 4.
This review examines the available evidence concerning the incidence of heart failure in patients with chronic coronary syndrome, with a focus on gender differences.
The incidence of heart failure in the context of chronic coronary syndrome presents conflicting data. Most of the available information stems from studies involving stable patients' post-acute coronary syndrome, revealing a wide range of incidence rates, from less than 3% to over 20%, observed over 5 years of follow-up. Regarding the gender differences in heart failure incidence, there is no consensus about whether women exhibit a higher incidence, particularly in the presence of evidence of obstructive coronary artery disease. However, in cases where obstructive coronary artery disease is absent, women may face a more unfavourable prognosis due to a higher prevalence of microvascular disease and heart failure with preserved ventricular function. The different profile of ischaemic heart disease in women difficult to establish differences in prognosis independently associated with female sex. Targeted investigations are essential to discern the incidence of heart failure in chronic coronary syndrome and explore potential gender-specific associations.
本文回顾了慢性冠状动脉综合征患者心力衰竭发生率的相关证据，重点关注了性别差异。
慢性冠状动脉综合征背景下心力衰竭的发生率存在相互矛盾的数据。大多数现有信息来自于急性冠状动脉综合征后稳定患者的研究，显示出在 5 年随访期间，发生率范围很广，从低于 3%到超过 20%。关于心力衰竭发生率的性别差异，女性是否表现出更高的发生率，特别是在存在阻塞性冠状动脉疾病证据的情况下，尚无共识。然而，在不存在阻塞性冠状动脉疾病的情况下，由于微血管疾病和射血分数保留的心力衰竭更为普遍，女性可能面临更不利的预后。女性缺血性心脏病的不同特征使得难以确定与女性性别独立相关的预后差异。有必要进行针对性研究以明确慢性冠状动脉综合征中心力衰竭的发生率，并探讨潜在的性别特异性关联。
