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中药在抗衰老和与衰老相关疾病中的潜在作用:当前的证据和观点。

Potential Effects of Traditional Chinese Medicine in Anti-Aging and Aging-Related Diseases: Current Evidence and Perspectives.

机构信息

Department of Medical, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, People's Republic of China.

Department of AIDS Clinical Research Center, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, People's Republic of China.

出版信息

Clin Interv Aging. 2024 May 1;19:681-693. doi: 10.2147/CIA.S447514. eCollection 2024.

DOI:10.2147/CIA.S447514
PMID:38706635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11070163/
Abstract

Aging and aging-related diseases present a global public health problem. Therefore, the development of efficient anti-aging drugs has become an important area of research. Traditional Chinese medicine is an important complementary and alternative branch of aging-related diseases therapy. Recently, a growing number of studies have revealed that traditional Chinese medicine has a certain delaying effect on the progression of aging and aging-related diseases. Here, we review the progress in research into using traditional Chinese medicine for aging and aging-related diseases (including neurodegenerative diseases, cardiovascular diseases, diabetes, and cancer). Furthermore, we summarize the potential mechanisms of action of traditional Chinese medicine and provide references for further studies on aging and aging-related diseases.

摘要

衰老及其相关疾病是一个全球性的公共健康问题。因此,开发有效的抗衰老药物已成为一个重要的研究领域。中医药是治疗衰老及其相关疾病的重要补充和替代分支。最近,越来越多的研究表明,中医药对延缓衰老和衰老相关疾病的进展具有一定的作用。在这里,我们综述了中医药在衰老及其相关疾病(包括神经退行性疾病、心血管疾病、糖尿病和癌症)研究中的进展。此外,我们总结了中医药的潜在作用机制,为进一步研究衰老及其相关疾病提供了参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7b8/11070163/13bf43fc3eb6/CIA-19-681-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7b8/11070163/9d09d1ea22ae/CIA-19-681-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7b8/11070163/13bf43fc3eb6/CIA-19-681-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7b8/11070163/9d09d1ea22ae/CIA-19-681-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7b8/11070163/13bf43fc3eb6/CIA-19-681-g0002.jpg

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3
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