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颈部副神经节瘤:一例罕见的伴有脊柱转移的病例。

Paraganglioma of the Neck: A Rare Case With Spinal Metastasis.

作者信息

McCormack Sean, Hamad Eyad, Hamad Amar

机构信息

Saint James School of Medicine, Cane Hall Road, Arnos Vale, Saint Vincent and the Grenadines.

Northwestern School of Medicine, Chicago, Illinois, USA.

出版信息

Case Rep Oncol Med. 2024 Apr 26;2024:2025115. doi: 10.1155/2024/2025115. eCollection 2024.

DOI:10.1155/2024/2025115
PMID:38706789
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11068453/
Abstract

Paragangliomas are rare neuroendocrine tumors that arise from the paraganglia, which are clusters of neuroendocrine cells associated with the autonomic nervous system. These tumors are commonly found in the adrenal medulla but can also occur in other locations outside the adrenal gland. Here, we present a case report of a slow-growing paraganglioma in the left neck with spinal metastasis in a 60-year-old man. This case highlights the importance of considering paraganglion tumors in the differential diagnosis of neck masses and the need for early diagnosis and management to prevent potential complications. Importantly, both the clinical picture and anatomical location of these tumors is important when determining treatment plans.

摘要

副神经节瘤是一种罕见的神经内分泌肿瘤,起源于副神经节,即与自主神经系统相关的神经内分泌细胞簇。这些肿瘤通常发生在肾上腺髓质,但也可发生在肾上腺以外的其他部位。在此,我们报告一例60岁男性左侧颈部生长缓慢的副神经节瘤伴脊柱转移的病例。该病例强调了在颈部肿块的鉴别诊断中考虑副神经节瘤的重要性,以及早期诊断和治疗以预防潜在并发症的必要性。重要的是,在确定治疗方案时,这些肿瘤的临床表现和解剖位置都很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a113/11068453/b0c458e9e4b9/CRIONM2024-2025115.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a113/11068453/d60a05a08ca6/CRIONM2024-2025115.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a113/11068453/b0c458e9e4b9/CRIONM2024-2025115.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a113/11068453/d60a05a08ca6/CRIONM2024-2025115.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a113/11068453/b0c458e9e4b9/CRIONM2024-2025115.002.jpg

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本文引用的文献

1
Silent pheochromocytoma and paraganglioma: Systematic review and proposed definitions for standardized terminology.无症状嗜铬细胞瘤和副神经节瘤:系统评价和标准化术语建议定义。
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Cost-Effectiveness Analysis of Ga DOTA-TATE PET/CT, In-Pentetreotide SPECT/CT and CT for Diagnostic Workup of Neuroendocrine Tumors.镓 DOTA-奥曲肽 PET/CT、碘[131I]美罗曲肽 SPECT/CT 和 CT 用于神经内分泌肿瘤诊断检查的成本效益分析
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Update on Pheochromocytoma and Paraganglioma from the SSO Endocrine and Head and Neck Disease Site Working Group, Part 2 of 2: Perioperative Management and Outcomes of Pheochromocytoma and Paraganglioma.来自 SSO 内分泌和头颈部疾病网站工作组的关于嗜铬细胞瘤和副神经节瘤的更新,第 2 部分,共 2 部分:嗜铬细胞瘤和副神经节瘤的围手术期管理和结果。
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Update on Pheochromocytoma and Paraganglioma from the SSO Endocrine/Head and Neck Disease-Site Work Group. Part 1 of 2: Advances in Pathogenesis and Diagnosis of Pheochromocytoma and Paraganglioma.来自 SSO 内分泌/头颈部疾病工作组的嗜铬细胞瘤和副神经节瘤更新。第 1 部分,共 2 部分:嗜铬细胞瘤和副神经节瘤发病机制和诊断的进展。
Ann Surg Oncol. 2020 May;27(5):1329-1337. doi: 10.1245/s10434-020-08220-3. Epub 2020 Feb 28.
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Pheochromocytoma and Paraganglioma.嗜铬细胞瘤和副神经节瘤。
N Engl J Med. 2019 Aug 8;381(6):552-565. doi: 10.1056/NEJMra1806651.
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Pheochromocytomas and Paragangliomas: New Developments with Regard to Classification, Genetics, and Cell of Origin.嗜铬细胞瘤和副神经节瘤:关于分类、遗传学及起源细胞的新进展
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Efficacy and Safety of Ablative Therapy in the Treatment of Patients with Metastatic Pheochromocytoma and Paraganglioma.消融治疗在转移性嗜铬细胞瘤和副神经节瘤患者治疗中的疗效与安全性
Cancers (Basel). 2019 Feb 7;11(2):195. doi: 10.3390/cancers11020195.
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Performance of Ga-DOTA-Conjugated Somatostatin Receptor-Targeting Peptide PET in Detection of Pheochromocytoma and Paraganglioma: A Systematic Review and Metaanalysis.镓-DOTA 偶联生长抑素受体靶向肽 PET 在嗜铬细胞瘤和副神经节瘤检测中的性能:系统评价和荟萃分析。
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