Dogani Manijeh, Askari Nayere, Hesari Ali Kalantari
Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran.
Immunoregulation Research Center, Shahed University, Tehran, Iran.
J Tradit Complement Med. 2023 Nov 28;14(3):335-342. doi: 10.1016/j.jtcme.2023.09.004. eCollection 2024 May.
Baneh () is a plant species that is commonly consumed as food and has a long-standing traditional use as a sexual enhancer. Despite its widespread use, a limited amount of academic and scientific literature is available regarding its potential impact on the reproductive system. The present research aimed to study the effect of a diet enriched with Baneh on the female rats' reproductive system.
Three groups of rats (n = 8) were subjected to the intended diet for six weeks. Subsequently, their histomorphometric parameters, sex hormone levels, as well as the expression of oxytocin (OXT) and oxytocin receptor (OXTR) genes were measured. The rats' serum vitamin D, zinc, and lipid profiles were also evaluated.
Results revealed that compared to the normal food, the diet containing 20 % Baneh significantly increased the progesterone and estradiol levels three and two times, respectively. It decreased the total body weight while increasing the ratio of ovary weight to the body weight. Furthermore, the Baneh-enriched diet raised HDL, zinc, and vitamin D levels, though it reduced the LDL and TG levels by 15 μg/dl and 24 μg/dl, respectively, and the concentration of ovary malondialdehyde decreased by 50 % in the treated group. Also, the diet increased the follicle graph, corpus luteum, the thickness of the epithelium, the number of endometrial glands, and the expression of both and genes. Our findings suggested that could considerably improve the female sex hormone levels and their reproductive system.
巴内(Baneh)是一种常被用作食物的植物物种,长期以来一直被传统地用作性增强剂。尽管其使用广泛,但关于其对生殖系统潜在影响的学术和科学文献数量有限。本研究旨在探讨富含巴内的饮食对雌性大鼠生殖系统的影响。
三组大鼠(n = 8)接受目标饮食六周。随后,测量它们的组织形态计量学参数、性激素水平以及催产素(OXT)和催产素受体(OXTR)基因的表达。还评估了大鼠血清中的维生素D、锌和血脂谱。
结果显示,与正常食物相比,含有20%巴内的饮食分别使孕酮和雌二醇水平显著提高了三倍和两倍。它降低了总体重,同时增加了卵巢重量与体重的比值。此外,富含巴内的饮食提高了高密度脂蛋白、锌和维生素D水平,尽管它分别使低密度脂蛋白和甘油三酯水平降低了15μg/dl和24μg/dl,且治疗组卵巢丙二醛浓度降低了50%。而且,该饮食增加了卵泡数量、黄体数量、上皮厚度、子宫内膜腺体数量以及OXT和OXTR基因的表达。我们的研究结果表明,巴内可以显著改善雌性激素水平及其生殖系统。