Ma Xiaoling, Wu Luming, Wang Yinxue, Han Shiqiang, El-Dalatony Marwa M, Feng Fei, Tao Zhongbin, Yu Liulin, Wang Yiqing
The First Hospital of Lanzhou University The First School of Clinical Medicine Lanzhou University Lanzhou China.
Gansu International Scientific and Technological Cooperation Base of Reproductive Medicine Transformation Application Key Laboratory for Reproductive Medicine and Embryo Lanzhou China.
Food Sci Nutr. 2022 Mar 21;10(5):1368-1384. doi: 10.1002/fsn3.2708. eCollection 2022 May.
Nutrition and lifestyle have a great impact on reproduction and infertility in humans, as they are essential for certain processes such as implantation, placental growth, angiogenesis, and the transfer of nutrients from the mother to the fetus. The aim of this review is to provide the interconnection between nutrition and reproductive health through the insight of omics approaches (including metabolomics and nutrigenomics). The effect of various macronutrients, micronutrients, and some food-associated components on male and female reproduction was discussed. Recent research work was collected through database search from 2010 to 2020 to identify eligible studies. Alterations of metabolic pathways in pregnant women were deliberated with an emphasis on different strategies of lifestyle and dietary interventions. Several nutritional methods, which are important for embryonic and child neurological development, nutritional supplements to lactation, and improved gestational length along with birth weight have been emphasized. Considerable advances in omics strategies show potential technological development for improving human reproductive health.
营养和生活方式对人类的生殖及不孕不育有着重大影响，因为它们对于某些过程至关重要，如着床、胎盘生长、血管生成以及营养物质从母体向胎儿的转运。本综述的目的是通过组学方法（包括代谢组学和营养基因组学）的洞察来揭示营养与生殖健康之间的相互联系。讨论了各种常量营养素、微量营养素以及一些与食物相关的成分对男性和女性生殖的影响。通过数据库搜索收集了2010年至2020年的近期研究工作，以确定符合条件的研究。探讨了孕妇代谢途径的改变，并重点关注生活方式和饮食干预的不同策略。强调了几种对胚胎和儿童神经发育、哺乳期营养补充以及改善妊娠期长度和出生体重很重要的营养方法。组学策略的显著进展显示了改善人类生殖健康的潜在技术发展。
