O'Toole Roger, Watson Dean
Melbourne Headache Centre, Melbourne, Victoria, 3000, Australia.
Allied Health and Human Performance, University of South Australia, Adelaide, South Australia, Australia.
Health Open Res. 2023 Aug 22;5:12. doi: 10.12688/healthopenres.13319.3. eCollection 2023.
Vestibular migraine (VM) is a relatively new diagnostic entity with incomplete knowledge regarding pathophysiological mechanisms and therapeutic guidelines. By reporting the effect of manual cervical therapy (MCT) on people with VM, we suggest a possible role for upper cervical afferents in VM treatment and/or pathogenesis. The objective was to describe the change in clinical presentation and self-reported symptoms of VM corresponding to MCT and followed up to six months.
A nonrandomised *ABA design was utilised to consecutively and prospectively evaluate selected patients with diagnosed VM. Symptom characteristics (frequency and intensity) were recorded along with standardised patient-reported outcomes (PROs) to document the response to MCT.
Three patients were recruited who met the diagnostic criteria for VM. All three patients demonstrated improvement in both migraine attack and interictal symptom frequency. These improvements mirrored changes in PROs and were sustained over a six-month follow-up period.
The improvement that coincided with the intervention including MCT was rapid, observable and sustained. This suggests that the upper cervical spine could be a therapeutic target in VM and may have implications for future research into the pathogenesis of VM.
前庭性偏头痛(VM)是一种相对较新的诊断实体,对其病理生理机制和治疗指南的了解尚不完整。通过报告手法颈部治疗(MCT)对VM患者的影响,我们提出上颈段传入神经在VM治疗和/或发病机制中可能发挥的作用。目的是描述与MCT相应的VM临床表现和自我报告症状的变化,并随访6个月。
采用非随机ABA设计,对确诊为VM的选定患者进行连续、前瞻性评估。记录症状特征(频率和强度)以及标准化的患者报告结局(PROs),以记录对MCT的反应。
招募了3名符合VM诊断标准的患者。所有3名患者的偏头痛发作和发作间期症状频率均有改善。这些改善反映了PROs的变化,并在6个月的随访期内持续存在。
与包括MCT在内的干预措施同时出现的改善迅速、可观察且持续。这表明上颈椎可能是VM的一个治疗靶点,可能对VM发病机制的未来研究产生影响。