Heilongjiang University of Chinese Medicine, Harbin, China.
First Affiliated Hospital Heilongjiang University of Chinese Medicine, Harbin, China.
PLoS One. 2024 May 6;19(5):e0300769. doi: 10.1371/journal.pone.0300769. eCollection 2024.
Post-stroke depression is a common complication of stroke, with a high incidence rate and low recognition rate. Many patients do not receive effective intervention at the onset, which affects subsequent treatment outcomes. Post-stroke depression not only impacts the patient's mental well-being but also increases the risk of stroke recurrence and poor prognosis. Therefore, it has become a significant public health concern. Acupuncture has gained significant popularity in the treatment of post-stroke depression. However, there are inconsistent clinical research results regarding its efficacy and safety. This systematic review aims to gather and critically assess all available evidence regarding the effectiveness and safety of acupuncture in the treatment of post-stroke depression in patients.
We will conduct thorough searches for relevant studies in multiple electronic databases (PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure, VIP Database, Wan-fang Data and China Biomedical Database). Our search scope will encompass studies published from the inception of each database until September 2023. To evaluate the potential bias in all the included studies, we will adhere to the guidelines offered in the Cochrane Handbook. The total effective rate will be the primary outcome. To conduct a systematic review, we will employ RevMan 5.4 software.
This study will obtain efficacy and safety of acupuncture for the treatment of post-stroke depression.
The conclusions of this study will provide evidence-based perspectives that can guide clinical decision-making regarding the practicality and recommended timing of using acupuncture to treat post-stroke depression. Furthermore, this study will help advance the clinical application of acupuncture treatment for post-stroke depression and enhance its efficacy while ensuring patient safety.
脑卒中后抑郁是脑卒中的常见并发症，发病率高，识别率低。许多患者在发病时得不到有效干预，影响后续的治疗效果。脑卒中后抑郁不仅影响患者的精神健康，而且增加了脑卒中复发和预后不良的风险。因此，它已成为一个重大的公共卫生问题。针刺在脑卒中后抑郁的治疗中得到了广泛的关注。然而，其疗效和安全性的临床研究结果并不一致。本系统评价旨在收集和批判性评估所有关于针刺治疗脑卒中后抑郁患者的有效性和安全性的现有证据。
我们将在多个电子数据库（PubMed、Embase、Cochrane 图书馆、中国知网、维普数据库、万方数据和中国生物医学文献数据库）中进行全面检索。我们的检索范围将包括从每个数据库建立到 2023 年 9 月发表的所有研究。为了评估所有纳入研究的潜在偏倚，我们将遵循 Cochrane 手册提供的指南。总有效率将作为主要结局。我们将使用 RevMan 5.4 软件进行系统评价。
本研究将获得针刺治疗脑卒中后抑郁的疗效和安全性。
本研究的结论将为临床决策提供基于证据的观点，指导针刺治疗脑卒中后抑郁的实用性和推荐时机。此外，本研究将有助于推进针刺治疗脑卒中后抑郁的临床应用，提高疗效，确保患者安全。
