Wentz Eryka, Ni Zhanmo, Yenokyan Karine, Vergara Candelaria, Pahwa Jessica, Kammerling Thea, Xiao Pu, Duggal Priya, Lau Bryan, Mehta Shruti H
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD.
medRxiv. 2024 Apr 26:2024.04.25.24306387. doi: 10.1101/2024.04.25.24306387.
COVID-19 disease continues to affect millions of individuals worldwide, both in the short and long term. The post-acute complications of SARS-CoV-2 infection, referred to as long COVID, result in diverse symptoms affecting multiple organ systems. Little is known regarding how the symptoms associated with long COVID progress and resolve over time. The Johns Hopkins COVID Long Study aims to prospectively examine the short- and long-term consequences of COVID-19 disease in individuals both with and without a history of SARS-CoV-2 infection using self-reported data collected in an online survey.
Sixteen thousand, seven hundred sixty-four adults with a history of SARS-CoV-2 infection and 799 adults without a history of SARS-CoV-2 infection who completed an online baseline survey.
This cohort profile describes the baseline characteristics of the Johns Hopkins COVID Long Study. Among 16,764 participants with a history of SARS-CoV-2 infection and defined long COVID status, 75% reported a good or excellent health status prior to infection, 99% reported experiencing at least one COVID-19 symptom during the acute phase of infection, 9.9% reported a hospitalization, and 63% were defined as having long COVID using the WHO definition.
Analysis of longitudinal data will be used to investigate the progression and resolution of long COVID symptoms over time.
新冠病毒病在短期和长期内持续影响着全球数百万人。SARS-CoV-2感染的急性后遗症，即“长新冠”，会导致影响多个器官系统的各种症状。关于“长新冠”相关症状如何随时间发展和缓解，目前知之甚少。约翰·霍普金斯新冠长期研究旨在通过在线调查收集的自我报告数据，前瞻性地研究有无SARS-CoV-2感染史的个体中新冠病毒病的短期和长期后果。
16764名有SARS-CoV-2感染史的成年人以及799名无SARS-CoV-2感染史的成年人，他们完成了在线基线调查。
本队列概况描述了约翰·霍普金斯新冠长期研究的基线特征。在16764名有SARS-CoV-2感染史且确定为“长新冠”状态的参与者中，75%报告在感染前健康状况良好或极佳，99%报告在感染急性期至少出现一种新冠病毒病症状，9.9%报告曾住院治疗，63%根据世界卫生组织的定义被确定为患有“长新冠”。
将利用纵向数据分析“长新冠”症状随时间的发展和缓解情况。
