Ismail Raghad M, Thomas Dixon, Jagdale Rajaram
Department of Pharmacy Practice, College of Pharmacy, Gulf Medical University, Ajman, United Arab Emirates.
Department of Nephrology, College of Medicine, Gulf Medical University, Ajman, United Arab Emirates.
Int J Crit Illn Inj Sci. 2024 Jan-Mar;14(1):32-36. doi: 10.4103/ijciis.ijciis_57_23. Epub 2024 Mar 27.
Multiple factors influence the fall risk in end-stage kidney disease. This study aims to investigate how medication factors influence the interpretation of fall risk due to age, gender, and years of dialysis treatment among patients undergoing hemodialysis (HD).
A cross-sectional study was carried out in 2023 using the Johns Hopkins Fall Risk Assessment tool. Participants were recruited from the HD unit at a tertiary care academic medical center in Ajman, UAE. Data were analyzed between different ages, genders, and years on HD categories with or without medication factors.
Data were collected and analyzed for 44 patients. The fall risk of the study population assessed with the Kruskal-Wallis test showed no difference between different age groups ( = 0.43) but did show a significant difference when the score of medication factor was removed from the fall risk estimation ( = 0.002). A pairwise analysis showed fall risk score of the age group 46-60 years was differing from the age cohort >60 ( < 0.001). A positive moderate correlation (Spearman's correlation coefficient 0.514 was found, with a < 0.001) was seen with an increase in age and fall risk only when the medication factor was removed from the fall risk estimation. Results on gender or duration of dialysis were insignificant.
Medication factors being a significant contributor to fall risk among the study population was found to mask the fall risk difference between age groups 46-60 years and >60 years. Such influence was not found for gender or duration of dialysis.
多种因素影响终末期肾病患者的跌倒风险。本研究旨在调查药物因素如何影响血液透析（HD）患者中因年龄、性别和透析治疗年限导致的跌倒风险评估。
2023年采用约翰霍普金斯跌倒风险评估工具进行了一项横断面研究。参与者从阿联酋阿治曼一家三级医疗学术医学中心的血液透析科招募。对有无药物因素的不同年龄、性别和血液透析年限类别的数据进行了分析。
收集并分析了44例患者的数据。用Kruskal-Wallis检验评估的研究人群跌倒风险在不同年龄组之间无差异（ = 0.43），但当从跌倒风险估计中去除药物因素得分时，差异显著（ = 0.002）。两两分析显示，46 - 60岁年龄组的跌倒风险评分与>60岁年龄组不同（ < 0.001）。仅在从跌倒风险估计中去除药物因素时，年龄增加与跌倒风险呈正相关且相关性中等（Spearman相关系数为0.514， < 0.001）。性别或透析时长的结果无统计学意义。
发现药物因素是研究人群跌倒风险的一个重要因素，它掩盖了46 - 60岁和>60岁年龄组之间的跌倒风险差异。未发现性别或透析时长有此类影响。
