一项评估枣糖浆、菠萝汁和补血糖浆作为磁共振口服造影剂在改善磁共振胰胆管造影图像质量中作用的研究。
A Study to Assess the Role of Date Syrup, Pineapple Juice, and Hematinic Syrup as Magnetic Resonance Oral Contrast Agents in Improving the Image Quality of Magnetic Resonance Cholangiopancreatography.
作者信息
R K Karpagam, Duvooru Sukumar Pujitha, Ravula Pranathi, Ramakrishnan Karthik Krishna, Haritha P Shree, Natarajan Paarthipan
机构信息
Department of Radiology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS) Saveetha University, Chennai, IND.
出版信息
Cureus. 2024 Apr 7;16(4):e57769. doi: 10.7759/cureus.57769. eCollection 2024 Apr.
INTRODUCTION
Magnetic resonance cholangiopancreatography (MRCP) is an imaging technique that has advanced over the past few years. It still plays a crucial role in the study of numerous pancreaticobiliary diseases. This study aimed to evaluate the effects of hematinic syrup, date syrup, and pineapple juice on MRCP image quality.
METHODOLOGY
This study involved a total of 90 participants, distributed evenly among three groups, with each group comprising 30 patients. Negative oral contrast solutions containing paramagnetic substances like Mn+2 and Fe+3, such as pineapple juice, date syrup, and hematinic syrup were imaged by 1.5 Tesla (T) magnetic resonance imaging (MRI) with T2-weighted (T2W) and MRCP sequences. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were computed. Ninety patients underwent MRCP 20-30 min after ingestion of 100 mL of date syrup, 30 ml of hematinic syrup diluted to 200 ml of water, and 200 mL of pineapple juice. MRCP images were taken to visualize various pancreaticobiliary structures (bile duct, stomach, and duodenum).
RESULTS
The in vitro evaluation of the solutions showed that date syrup and hematinic syrup were hypointense in T2W sequences. The images obtained showed no significant difference in the CNR between the three solutions. However, the SNR was significantly higher for pineapple juice compared to date syrup and hematinic syrup in T2W and MRCP sequences. Images acquired post-administration of the oral contrast agents significantly improved the gastrointestinal tract signal suppression and increased visibility of the pancreaticobiliary structures (bile duct, stomach, and duodenum). No adverse events were observed among the participants.
CONCLUSION
Pineapple juice was the best contrast agent. However, date syrup and hematinic syrup can also be used to improve the imaging quality.
引言
磁共振胰胆管造影（MRCP）是一种在过去几年中不断发展的成像技术。它在众多胰腺和胆道疾病的研究中仍发挥着关键作用。本研究旨在评估补血糖浆、枣糖浆和菠萝汁对MRCP图像质量的影响。
方法
本研究共纳入90名参与者，平均分为三组，每组30例患者。使用含顺磁性物质如Mn+2和Fe+3的阴性口服对比剂，如菠萝汁、枣糖浆和补血糖浆，通过1.5特斯拉（T）磁共振成像（MRI）的T2加权（T2W）和MRCP序列进行成像。计算信噪比（SNR）和对比噪声比（CNR）。90名患者在摄入100 mL枣糖浆、30 mL补血糖浆稀释至200 mL水和200 mL菠萝汁后20 - 30分钟接受MRCP检查。拍摄MRCP图像以观察各种胰腺和胆道结构（胆管、胃和十二指肠）。
结果
溶液的体外评估显示，枣糖浆和补血糖浆在T2W序列中呈低信号。获得的图像显示三种溶液之间的CNR无显著差异。然而，在T2W和MRCP序列中，菠萝汁的SNR显著高于枣糖浆和补血糖浆。口服对比剂给药后获得的图像显著改善了胃肠道信号抑制，并增加了胰腺和胆道结构（胆管、胃和十二指肠）的可见性。参与者中未观察到不良事件。
结论
菠萝汁是最佳对比剂。然而，枣糖浆和补血糖浆也可用于提高成像质量。
Zotero 插件