Zhonghua Xue Ye Xue Za Zhi. 2024 Mar 14;45(3):209-214. doi: 10.3760/cma.j.cn121090-20231107-00252.
Primary mediastinal large B-cell lymphoma (PMBL) is an aggressive B-cell lymphoma that is thought to arise from thymic (medullary) B cells and has unique clinicopathologic and molecular features. In recent years, the understanding of the pathogenesis and treatment of PMBL has been updated to varying degrees, particularly in the area of new drug therapy. In order to improve the diagnosis and treatment of PMBL in China, the Lymphocyte Disease Group of the Chinese Medical Association (CMA) and the Anti-Lymphoma Alliance of the Chinese Society of Clinical Oncology (CSCO) commissioned a group of experts to formulate this consensus.
原发性纵隔大B细胞淋巴瘤（PMBL）是一种侵袭性B细胞淋巴瘤，被认为起源于胸腺（髓质）B细胞，具有独特的临床病理和分子特征。近年来，对PMBL发病机制和治疗的认识有了不同程度的更新，尤其是在新药治疗领域。为提高我国PMBL的诊断和治疗水平，中华医学会淋巴细胞疾病学组和中国临床肿瘤学会（CSCO）抗淋巴瘤联盟委托一组专家制定本共识。
