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不可分型流感嗜血杆菌的外膜蛋白以及感染患者配对血清与其同源分离株的反应性。

Outer membrane proteins of nontypable Haemophilus influenzae and reactivity of paired sera from infected patients with their homologous isolates.

作者信息

Hansen M V, Musher D M, Baughn R E

出版信息

Infect Immun. 1985 Mar;47(3):843-6. doi: 10.1128/iai.47.3.843-846.1985.

DOI:10.1128/iai.47.3.843-846.1985
PMID:3871735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC261407/
Abstract

Normal human serum and acute or convalescent serum from patients infected with nontypable Haemophilus influenzae were tested for reactivity with electroblotted outer membrane proteins obtained from the homologous nontypable H. influenzae isolates. Of 12 patients, 8 had immunoglobulin G antibodies to outer membrane proteins from their own infecting nontypable H. influenzae isolates that were not present in normal human serum. Three patients had immunoglobulin antibody in convalescent serum that had been absent in acute serum, but no consistent outer membrane protein was involved in the sets of patient sera with outer membrane proteins examined.

摘要

对正常人血清以及感染了不可分型流感嗜血杆菌的患者的急性期或恢复期血清,检测其与从同源不可分型流感嗜血杆菌分离株获得的电印迹外膜蛋白的反应性。在12名患者中,8名患者具有针对自身感染的不可分型流感嗜血杆菌分离株外膜蛋白的免疫球蛋白G抗体,而正常人血清中不存在这些抗体。3名患者恢复期血清中有急性期血清中未出现的免疫球蛋白抗体,但在所检测的患者血清与外膜蛋白组合中,没有涉及一致的外膜蛋白。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/573e/261407/dd87e736a789/iai00120-0272-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/573e/261407/dd87e736a789/iai00120-0272-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/573e/261407/dd87e736a789/iai00120-0272-a.jpg

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