口服右美托咪定诱导猫呕吐的应用。
Use of orally administered dexmedetomidine to induce emesis in cats.
机构信息
Department of Small Animal Clinical Sciences, University of Florida, Gainesville, FL, USA.
出版信息
J Feline Med Surg. 2024 May;26(5):1098612X241248980. doi: 10.1177/1098612X241248980.
CASE SERIES SUMMARY
This case series describes the use of orally administered dexmedetomidine at a dose of 20 µg/kg to induce emesis in six cats. Emesis was successfully induced in 5/6 cats, with each of the cats vomiting once. The reasons for inducing vomiting included known or suspected ingestion of lilies, onions, acetaminophen (paracetamol) or acetylsalicylic acid. Four of the five cats in which emesis induction was successful did not develop any clinical signs of toxicity associated with the toxin ingested; the fifth cat developed clinicopathological changes consistent with acetaminophen toxicity. All six cats exhibited moderate to profound sedation, as expected, but no other adverse effects were documented.
RELEVANCE AND NOVEL INFORMATION
Induction of emesis in cats is notoriously difficult. This case series describes a novel route of administration of dexmedetomidine, a commonly available medication, with a high success rate observed for inducing emesis in this group of cats.
病例系列总结
本病例系列描述了使用口服右美托咪定 20µg/kg 剂量诱导 6 只猫呕吐的情况。在 6 只猫中有 5 只成功诱导呕吐，每只猫呕吐一次。诱导呕吐的原因包括已知或疑似摄入百合、洋葱、对乙酰氨基酚（扑热息痛）或乙酰水杨酸。在成功诱导呕吐的 5 只猫中，有 4 只没有出现与摄入毒素相关的任何毒性的临床症状；第 5 只猫出现了与对乙酰氨基酚毒性一致的临床病理变化。所有 6 只猫都表现出中度至深度镇静，这是预期的，但没有记录到其他不良反应。
相关性和新颖信息
在猫中诱导呕吐是出了名的困难。本病例系列描述了一种新的右美托咪定给药途径，这是一种常用药物，在该组猫中观察到诱导呕吐的成功率很高。
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