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正常和恶性人类白细胞表面糖蛋白(S-GP)

Surface glycoproteins (S-GP) on normal and malignant human leukocytes.

作者信息

Leiter E, Pfister R, Lutz D, Michlmayr G, Gadner H, Gattringer C, Schmalzl F, Braunsteiner H, Huber C

出版信息

Blut. 1985 Mar;50(3):157-68. doi: 10.1007/BF00320072.

Abstract

This study aimed to investigate high molecular weight surface glycoprotein (S-GP) patterns on various types of human leukocytes. S-GP were externally labelled by the Galactose-oxidase-NaB3H4 technique. Results based on the analysis of 120 samples derived from different types of normal and malignant leukocytes indicate that the relative expression of high molecular weight S-GPs changes during haemopoietic cell differentiation and to some extent these changes enable the classification of human leukocytes.

摘要

本研究旨在调查各类人类白细胞上的高分子量表面糖蛋白(S-GP)模式。采用半乳糖氧化酶-NaB3H4技术对S-GP进行外部标记。基于对120份来自不同类型正常和恶性白细胞样本的分析结果表明,高分子量S-GP的相对表达在造血细胞分化过程中发生变化,并且这些变化在一定程度上能够对人类白细胞进行分类。

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