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瑞典男性中冠心病死亡率不断上升。

Increasing mortality from coronary heart disease among males in Sweden.

作者信息

Welin L, Wilhelmsen L, Svärdsudd K, Larsson B, Tibblin G

出版信息

Cardiology. 1985;72(1-2):75-80. doi: 10.1159/000173846.

DOI:10.1159/000173846
PMID:3872176
Abstract

In Sweden, coronary heart disease (CHD) mortality increased by 30% among 50- to 54-year-old men and by 20% among 55- to 59-year-old men between 1968 and 1980. Among women there was no change during the same time. Two cohorts of 50-year-old men living in Gothenburg, Sweden, were examined 10 years apart (1963-1973): Levels of the 3 major CHD risk factors, blood pressure, serum cholesterol and smoking habits, were similar in these two cohorts. Men in the latest examined cohort had almost doubled the 7-year incidence of fatal and non-fatal CHD compared to men in the first examined cohort. Obesity was more prevalent among men examined in 1973 and also a significant risk factor for CHD in that cohort. Increased obesity and very slightly increased serum cholesterol levels can, however, only explain part of the increased incidence of CHD. Hypertension is being more effectively treated, the prevalence of smokers has decreased, and treatment of symptomatic CHD is similarly active in Sweden as in many other countries. Thus, several changes largely parallel those taking place in countries with decreasing CHD mortality. In spite of this, CHD mortality is increasing among males in Sweden. Possible reasons for this are discussed.

摘要

在瑞典,1968年至1980年间,50至54岁男性的冠心病(CHD)死亡率上升了30%,55至59岁男性的冠心病死亡率上升了20%。而在同一时期,女性的冠心病死亡率没有变化。对瑞典哥德堡的两组相隔10年(1963年至1973年)接受检查的50岁男性进行研究发现:这两组人群中,三种主要的冠心病风险因素,即血压、血清胆固醇和吸烟习惯的水平相似。与第一组接受检查的男性相比,最近一组接受检查的男性发生致命和非致命冠心病的7年发病率几乎翻了一番。肥胖在1973年接受检查的男性中更为普遍,并且也是该组中冠心病的一个重要风险因素。然而,肥胖增加和血清胆固醇水平非常轻微的升高只能部分解释冠心病发病率的增加。高血压得到了更有效的治疗,吸烟者的比例有所下降,而且瑞典对有症状冠心病的治疗与许多其他国家一样积极。因此,瑞典发生的一些变化在很大程度上与冠心病死亡率下降的国家所发生的变化相似。尽管如此,瑞典男性的冠心病死亡率仍在上升。本文对其可能的原因进行了讨论。

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