Nanoscience and Technology Program, Graduate School, Chulalongkorn University, Phayathai Road, Pathumwan, Bangkok 10330, Thailand.
Department of Fiber Science, College of Human Ecology, Cornell University, Ithaca, NY 14850, United States.
Int J Biol Macromol. 2024 Jun;269(Pt 2):132185. doi: 10.1016/j.ijbiomac.2024.132185. Epub 2024 May 7.
Natural fiber has become one of the most widely used alternative materials for chemical sensor fabrication due to its advantages, such as biocompatibility, flexibility, and self-microfluidic properties. Enhanced natural fiber surface has been used as a substrate in colorimetric and electrochemical sensors. This review focuses on improving the natural fiber properties for preparation as a substrate for chemical sensors. Various methods for natural fiber extraction are discussed and compared. Bleaching and decolorization is important for preparation of colorimetric sensors, while carbonization and nanoparticle doping are favorable for increasing their electrical conductivity for electrochemical sensor fabrication. Also, example fabrications and applications of natural fiber-based chemical sensors for chemical and biomarker detection are discussed. The selectivity of the sensors can be introduced and improved by surface modification of natural fiber, such as enzyme immobilization and biorecognition element functionalization, illustrating the adaptability of natural fiber as a smart sensing device, e.g., wearable and portable sensors. Ultimately, the high performances of natural fiber-based chemical sensors indicate the potential uses of natural fiber as a renewable and eco-friendly substrate material in the field of chemical sensors and biosensors for clinical diagnosis and environmental monitoring.
天然纤维因其生物相容性、柔韧性和自微流控特性等优点，已成为化学传感器制造中最广泛使用的替代材料之一。增强的天然纤维表面已被用作比色和电化学传感器的基底。本综述重点介绍了改善天然纤维性能，以制备化学传感器的基底。讨论并比较了各种天然纤维提取方法。漂白和脱色对于制备比色传感器很重要，而碳化和纳米颗粒掺杂有利于提高其电导率，以用于电化学传感器的制造。此外，还讨论了基于天然纤维的化学传感器在化学和生物标志物检测方面的示例制作和应用。通过天然纤维的表面改性（如酶固定化和生物识别元件功能化）可以引入和改善传感器的选择性，例如可穿戴和便携式传感器，展示了天然纤维作为智能传感装置的适应性。最终，基于天然纤维的化学传感器的高性能表明，天然纤维作为可再生和环保的基底材料在化学传感器和生物传感器领域具有潜在的应用前景，可用于临床诊断和环境监测。
