Metallurgy and Materials Science Research Institute, Chulalongkorn University, Soi Chula 12, Phayathai Road, Pathumwan, Bangkok, 10330, Thailand.
Department of Materials and Textile Technology, Faculty of Science and Technology, Thammasat University, Patumtani, 12120, Thailand.
Anal Chim Acta. 2021 Sep 22;1179:338643. doi: 10.1016/j.aca.2021.338643. Epub 2021 May 14.
Over the past decade, non-invasive wearable chemical sensors have gained tremendous attention in the field of personal health monitoring and medical diagnosis. These sensors provide non-invasive, real-time, and continuous monitoring of targeted biomarkers with more simplicity than the conventional diagnostic approaches. This review primarily describes the substrate materials used for sensor fabrication, sample collection and handling, and analytical detection techniques that are utilized to detect biomarkers in different biofluids. Common substrates including paper, textile, and hydrogel for wearable sensor fabrication are discussed. Principles and applications of colorimetric and electrochemical detection in wearable chemical sensors are illustrated. Data transmission systems enabling wireless communication between the sensor and output devices are also discussed. Finally, examples of different designs of wearable chemical sensors including tattoos, garments, and accessories are shown. Successful development of non-invasive wearable chemical sensors will effectively help users to manage their personal health, predict the potential diseases, and eventually improve the overall quality of life.
在过去的十年中，非侵入式可穿戴化学传感器在个人健康监测和医学诊断领域引起了极大的关注。与传统诊断方法相比，这些传感器能够更简单地对目标生物标志物进行非侵入式、实时和连续监测。本综述主要描述了用于传感器制造、样品采集和处理以及分析检测技术的基底材料，这些技术用于检测不同生物流体中的生物标志物。讨论了用于可穿戴传感器制造的常见基底材料，包括纸张、纺织品和水凝胶。阐述了可穿戴化学传感器中比色法和电化学检测的原理和应用。还讨论了能够在传感器和输出设备之间实现无线通信的数据传输系统。最后，展示了不同设计的可穿戴化学传感器的示例，包括纹身、服装和配饰。成功开发非侵入式可穿戴化学传感器将有效地帮助用户管理个人健康、预测潜在疾病，并最终提高整体生活质量。
