碘染色纹理和颜色增强成像下食管鳞状细胞癌的可视性

Visibility of esophageal squamous cell carcinoma under iodine staining on texture and color enhancement imaging.

作者信息

Kato Tsunetaka, Hikichi Takuto, Nakamura Jun, Hashimoto Minami, Kobashi Ryoichiro, Yanagita Takumi, Takagi Tadayuki, Suzuki Rei, Sugimoto Mitsuru, Asama Hiroyuki, Sato Yuki, Shioya Yasuo, Kobayakawa Masao, Ohira Hiromasa

机构信息

Department of Endoscopy Fukushima Medical University Hospital Fukushima Japan.

Department of Gastroenterology Fukushima Medical University School of Medicine Fukushima Japan.

出版信息

DEN Open. 2024 May 8;5(1):e370. doi: 10.1002/deo2.370. eCollection 2025 Apr.

DOI:10.1002/deo2.370

PMID:38725874

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11079435/

Abstract

OBJECTIVE

Iodine staining on white light imaging (WLI) is the gold standard for detecting and demarcating esophageal squamous cell carcinoma (ESCC). We examined the effects of texture and color enhancement imaging (TXI) on improving the endoscopic visibility of ESCC under iodine staining.

METHODS

Twenty ESCC lesions that underwent endoscopic submucosal dissection were retrospectively included. The color difference between ESCC and the surrounding mucosa (e) on WLI, TXI, and narrow-band imaging was assessed, and e under 1% iodine staining on WLI and TXI. Furthermore, the visibility grade determined by endoscopists was evaluated on each imaging.

RESULT

The median e was greater on TXI than on WLI (14.53 vs. 10.71, respectively; < 0.005). Moreover, the median e on TXI under iodine staining was greater than the median e on TXI and narrow-band imaging (39.20 vs. 14.53 vs. 16.42, respectively; < 0.005 for both). A positive correlation in e under iodine staining was found between TXI and WLI (correlation coefficient = 0.61, < 0.01). Moreover, e under iodine staining on TXI in each lesion was greater than the corresponding e on WLI. The visibility grade assessed by endoscopists on TXI was also significantly greater than that on WLI under iodine staining ( < 0.01).

CONCLUSIONS

The visibility of ESCC after iodine staining was greater on TXI than on WLI.

摘要

目的

白光成像（WLI）下的碘染色是检测和划定食管鳞状细胞癌（ESCC）的金标准。我们研究了纹理和颜色增强成像（TXI）对改善碘染色下ESCC内镜可视性的影响。

方法

回顾性纳入20例接受内镜黏膜下剥离术的ESCC病变。评估WLI、TXI和窄带成像下ESCC与周围黏膜之间的色差（e），以及WLI和TXI下1%碘染色时的e。此外，评估内镜医师在每种成像上确定的可视等级。

结果

TXI上的e中位数大于WLI（分别为14.53和10.71；<0.005）。此外，碘染色下TXI的e中位数大于TXI和窄带成像下的e中位数（分别为39.20、14.53和16.42；两者均<0.005）。发现TXI和WLI在碘染色下的e呈正相关（相关系数=0.61，<0.01）。此外，每个病变TXI上碘染色下的e大于WLI上相应的e。内镜医师在TXI上评估的可视等级在碘染色下也显著高于WLI（<0.01）。