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用于即时检测的基于磁性纳米颗粒的生物传感器的进展。

Advancements in magnetic nanoparticle-based biosensors for point-of-care testing.

作者信息

Wang Miaomiao, Jin Lian, Hang-Mei Leung Polly, Wang-Ngai Chow Franklin, Zhao Xiaoni, Chen Hui, Pan Wenjing, Liu Hongna, Li Song

机构信息

Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, China.

Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.

出版信息

Front Bioeng Biotechnol. 2024 Apr 25;12:1393789. doi: 10.3389/fbioe.2024.1393789. eCollection 2024.

DOI:10.3389/fbioe.2024.1393789
PMID:38725992
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11079239/
Abstract

The significance of point-of-care testing (POCT) in early clinical diagnosis and personalized patient care is increasingly recognized as a crucial tool in reducing disease outbreaks and improving patient survival rates. Within the realm of POCT, biosensors utilizing magnetic nanoparticles (MNPs) have emerged as a subject of substantial interest. This review aims to provide a comprehensive evaluation of the current landscape of POCT, emphasizing its growing significance within clinical practice. Subsequently, the current status of the combination of MNPs in the Biological detection has been presented. Furthermore, it delves into the specific domain of MNP-based biosensors, assessing their potential impact on POCT. By combining existing research and spotlighting pivotal discoveries, this review enhances our comprehension of the advancements and promising prospects offered by MNP-based biosensors in the context of POCT. It seeks to facilitate informed decision-making among healthcare professionals and researchers while also promoting further exploration in this promising field of study.

摘要

即时检验（POCT）在早期临床诊断和个性化患者护理中的重要性日益得到认可，它已成为减少疾病爆发和提高患者生存率的关键工具。在即时检验领域，利用磁性纳米颗粒（MNPs）的生物传感器已成为备受关注的课题。本综述旨在全面评估即时检验的当前状况，强调其在临床实践中日益增长的重要性。随后，介绍了磁性纳米颗粒在生物检测中的结合现状。此外，还深入探讨了基于磁性纳米颗粒的生物传感器的特定领域，评估了它们对即时检验的潜在影响。通过结合现有研究并突出关键发现，本综述加深了我们对基于磁性纳米颗粒的生物传感器在即时检验背景下的进展和前景的理解。它旨在促进医疗保健专业人员和研究人员做出明智的决策，同时也推动在这个有前景的研究领域进行进一步探索。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/8676608de62c/fbioe-12-1393789-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/580d39707455/fbioe-12-1393789-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/9991b15219fd/fbioe-12-1393789-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/6aca7b0b4d1f/fbioe-12-1393789-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/3f972166140f/fbioe-12-1393789-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/41ee58b0b33b/fbioe-12-1393789-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/2280102fea06/fbioe-12-1393789-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/c5cce820c4cc/fbioe-12-1393789-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/c84b3323a4c7/fbioe-12-1393789-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/8676608de62c/fbioe-12-1393789-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/580d39707455/fbioe-12-1393789-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/9991b15219fd/fbioe-12-1393789-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/6aca7b0b4d1f/fbioe-12-1393789-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/3f972166140f/fbioe-12-1393789-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/41ee58b0b33b/fbioe-12-1393789-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/2280102fea06/fbioe-12-1393789-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/c5cce820c4cc/fbioe-12-1393789-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/c84b3323a4c7/fbioe-12-1393789-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375d/11079239/8676608de62c/fbioe-12-1393789-g009.jpg

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