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基于带有四分之一外部电极的压电管的内窥式光学相干断层扫描探头设计。

Design of an endoscopic OCT probe based on piezoelectric tube with quartered outside electrodes.

作者信息

Hu Jinyuan, Wu Sujian, Shi Guohua, Fan Jinyu, Yu Haoyang, Chen Sixu

机构信息

School of Biomedical Engineering (Suzhou), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

Jiangsu Province Key Laboratory of Medical Optics, Suzhou Institute of Biomedical Engineering and Technology Chinese Academy of Science, Suzhou, China.

出版信息

Front Bioeng Biotechnol. 2024 Apr 24;12:1391630. doi: 10.3389/fbioe.2024.1391630. eCollection 2024.

Abstract

Optical coherence tomography (OCT) is a pivotal imaging modality in ophthalmology for real-time, visualization of retinal structures. To enhance the capability and safety of OCT, this study focuses on the development of a micro intraocular OCT probe. The demand for minimal invasiveness and precise imaging drives the need for advanced probe designs that can access tight and sensitive areas, such as the ocular sclera. A novel OCT probe was engineered using a piezoelectric tube with quartered electrodes to drive Lissajous scanning movements at the end of a single-mode fiber. This design allows the probe to enter the eyeball through a scleral opening. Structural innovation enables the outer diameter of the endoscopic OCT probe to be adjusted from 13G (2.41 mm) to 25G (0.51 mm), accommodating various imaging field sizes and ensuring compatibility with different scleral incisions. The fabricated micro intraocular OCT probe successfully performed preliminary imaging experiments on fingers. The Lissajous scanning facilitated comprehensive coverage of the target area, enhancing the imaging capabilities. The integration of a piezoelectric tube with quartered outside electrodes into the OCT probe design proved effective for achieving precise control over scanning movements and adaptability to different surgical needs. The design characteristics and practical applications demonstrated the probe's potential in clinical settings.

摘要

光学相干断层扫描(OCT)是眼科用于实时可视化视网膜结构的关键成像方式。为提高OCT的性能和安全性,本研究聚焦于微型眼内OCT探头的开发。对微创性和精确成像的需求推动了对先进探头设计的需求,这种设计能够进入眼部巩膜等狭小且敏感的区域。一种新型OCT探头采用了带有四分之一电极的压电管进行设计,以在单模光纤末端驱动李萨如扫描运动。这种设计使探头能够通过巩膜开口进入眼球。结构创新使内窥式OCT探头的外径能够从13G(2.41毫米)调整到25G(0.51毫米),以适应各种成像视野大小,并确保与不同的巩膜切口兼容。所制造的微型眼内OCT探头成功地在手指上进行了初步成像实验。李萨如扫描有助于全面覆盖目标区域,增强了成像能力。将带有外部四分之一电极的压电管集成到OCT探头设计中,被证明对于实现对扫描运动的精确控制以及适应不同的手术需求是有效的。设计特点和实际应用证明了该探头在临床环境中的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3f2/11080653/c4540c74090d/fbioe-12-1391630-g001.jpg

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