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微型实时术中前向成像光学相干断层扫描探头

Miniature real-time intraoperative forward-imaging optical coherence tomography probe.

作者信息

Joos Karen M, Shen Jin-Hui

机构信息

Vanderbilt Eye Institute, Vanderbilt University, 2311 Pierce Avenue, Nashville, TN 37232, USA.

出版信息

Biomed Opt Express. 2013 Jul 16;4(8):1342-50. doi: 10.1364/BOE.4.001342. eCollection 2013.

DOI:10.1364/BOE.4.001342
PMID:24009997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3756577/
Abstract

Optical coherence tomography (OCT) has a tremendous global impact upon the ability to diagnose, treat, and monitor eye diseases. A miniature 25-gauge forward-imaging OCT probe with a disposable tip was developed for real-time intraoperative ocular imaging of posterior pole and peripheral structures to improve vitreoretinal surgery. The scanning range was 2 mm when the probe tip was held 3-4 mm from the tissue surface. The axial resolution was 4-6 µm and the lateral resolution was 25-35 µm. The probe was used to image cellophane tape and multiple ocular structures.

摘要

光学相干断层扫描(OCT)对眼部疾病的诊断、治疗和监测能力产生了巨大的全球影响。为了改善玻璃体视网膜手术,研发了一种带有一次性探头尖端的微型25G前向成像OCT探头,用于后极部和周边结构的实时术中眼部成像。当探头尖端距组织表面3 - 4毫米时,扫描范围为2毫米。轴向分辨率为4 - 6微米,横向分辨率为25 - 35微米。该探头用于对玻璃纸胶带和多个眼部结构进行成像。

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Preclinical evaluation and intraoperative human retinal imaging with a high-resolution microscope-integrated spectral domain optical coherence tomography device.高分辨率显微镜集成谱域光学相干断层扫描设备的临床前评估和术中人视网膜成像。
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